C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: NUAK family, SNF1-like kinase, 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000020032 Nuak1 10090 - 10:84370905-84440597 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000020220 Nuak1-001 84370905-84440597 protein_coding
  ENSMUST00000129355 Nuak1-002 84375296-84392388 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000020220
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000020220 4.514±1.32 3.894±0.58 3.538±0.31 10.796±3.05 3.957±1.48 1.405±0.46 3.593±0.49 2.899±0.83 0.511±0.30 10.820±0.88 3.260±1.40 8.666±4.01 3.184±2.06 0.444±0.22

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00021S CIL_00021S_0002 CGP 10:83722865-84440597
CIL_00021I CIL_00021I_0002 CGP 10:84370905-84534036

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002039 IEA p53 binding
GO:0004674 ISS protein serine/threonine kinase activity
GO:0005515 IEA protein binding
GO:0005524 IEA ATP binding
GO:0005634 ISS nucleus
GO:0005730 IEA nucleolus
GO:0005737 ISS cytoplasm
GO:0006468 IEA protein phosphorylation
GO:0006974 IEA cellular response to DNA damage stimulus
GO:0007155 IEA cell adhesion
GO:0015630 IEA microtubule cytoskeleton
GO:0030155 ISS regulation of cell adhesion
GO:0035507 ISS regulation of myosin-light-chain-phosphatase activity
GO:2000772 ISS regulation of cellular senescence

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000020086 NUAK1 (1 of 2) NUAK family, SNF1-like kinase, 1 protein_coding Danio_rerio
ENSDARG00000028676 NUAK1 (2 of 2) NUAK family, SNF1-like kinase, 1 protein_coding Danio_rerio
ENSG00000074590 NUAK1 NUAK family, SNF1-like kinase, 1 protein_coding Homo_sapiens

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