C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: SHC (Src homology 2 domain containing) transforming protein 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000020312 Shc2 10090 - 10:79617940-79637918 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000020564 Shc2-001 79618652-79637918 protein_coding
  ENSMUST00000163867 Shc2-201 79617940-79637918 protein_coding
  ENSMUST00000166450 Shc2-003 79620091-79623080 retained_intron
  ENSMUST00000168116 Shc2-002 79618051-79622724 retained_intron

Mus musculus EnsemblGRCm38

Genome
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Genes
Gene structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000020564ENSMUST00000163867ENSMUST00000168116
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000020564 2.490±1.42 1.616±0.57 0.930±0.34 7.401±2.22 3.138±1.58 1.284±0.59 0.392±0.01 0.291±0.07 0.082±0.06 0.622±0.30 1.497±0.61 3.901±1.57 0.646±0.48 1.216±0.30
ENSMUST00000163867 4.558±1.86 1.514±0.61 1.201±0.36 6.973±0.31 2.203±0.79 1.029±0.27 0.652±0.18 0.302±0.10 0.054±0.02 0.250±0.06 1.683±0.21 3.356±1.41 0.549±0.24 1.092±0.20
ENSMUST00000168116 2.109±0.09 N/A 0.521±0.03 3.420±0.00 0.807±0.00 N/A 0.213±0.04 0.112±0.04 0.033±0.01 N/A N/A 0.611±0.20 0.153±0.02 0.573±0.03

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008XG CIL_0008XG_0002 VISTA 10:79539861-80142369
CIL_0005CP CIL_0005CP_0002 CGP 10:79606857-79637918
CIL_0007I4 CIL_0007I4_0002 CGP 10:79617940-79645738

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000187 IEA activation of MAPK activity
GO:0030971 IEA receptor tyrosine kinase binding
GO:0035556 IEA intracellular signal transduction

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000062080 shc2 SHC (Src homology 2 domain containing) transforming protein 2 protein_coding Danio_rerio
ENSG00000129946 SHC2 SHC (Src homology 2 domain containing) transforming protein 2 protein_coding Homo_sapiens

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