C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: Kruppel-like factor 11
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000020653 Klf11 10090 + 12:24651371-24662774 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000020982 Klf11-001 24651371-24662774 protein_coding
  ENSMUST00000139940 Klf11-003 24651896-24653810 protein_coding
  ENSMUST00000144046 Klf11-004 24652154-24655137 protein_coding
  ENSMUST00000146894 Klf11-002 24651896-24655142 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000020982
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000020982 5.372±0.47 7.770±0.21 5.861±0.52 4.234±2.41 4.418±1.36 3.715±0.21 2.827±0.22 2.885±0.62 3.315±1.71 13.494±1.34 0.815±0.23 13.542±3.91 7.330±1.97 1.272±0.52

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007DG CIL_0007DG_0002 CGP 12:24572287-24662774
CIL_0007DF CIL_0007DF_0002 CGP 12:24651371-24681813

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000083 IEA regulation of transcription involved in G1/S transition of mitotic cell cycle
GO:0000122 IEA negative regulation of transcription from RNA polymerase II promoter
GO:0000981 IEA sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0003677 ISS DNA binding
GO:0003700 IDA sequence-specific DNA binding transcription factor activity
GO:0005634 IC nucleus
GO:0006915 IEA apoptotic process
GO:0008285 IEA negative regulation of cell proliferation
GO:0043065 IEA positive regulation of apoptotic process
GO:0044212 IEA transcription regulatory region DNA binding
GO:0045892 IDA negative regulation of transcription, DNA-templated
GO:0046872 IEA metal ion binding
GO:1901653 IEA cellular response to peptide

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000013794 klf11b Kruppel-like factor 11b protein_coding Danio_rerio
ENSDARG00000030844 klf11a Kruppel-like factor 11a protein_coding Danio_rerio
ENSG00000172059 KLF11 Kruppel-like factor 11 protein_coding Homo_sapiens

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