C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: purinergic receptor P2X, ligand-gated ion channel, 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000020787 P2rx1 10090 + 11:72999103-73015200 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000021141 P2rx1-001 72999103-73015200 protein_coding
  ENSMUST00000092938 P2rx1-002 72999315-73014126 protein_coding
  ENSMUST00000148964 P2rx1-003 73009791-73015197 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000021141ENSMUST00000092938ENSMUST00000148964
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000021141 1.872±0.27 0.309±0.20 282.261±28.35 0.090±0.02 0.659±0.28 0.484±0.21 0.269±0.07 1.655±0.35 2.519±2.12 1.220±0.36 0.251±0.06 0.501±0.18 1.671±1.56 1.990±1.35
ENSMUST00000092938 N/A N/A N/A 0.041±0.00 N/A N/A N/A N/A N/A N/A N/A 0.244±0.02 1.837±0.00 0.060±0.00
ENSMUST00000148964 0.509±0.15 0.256±0.00 N/A 0.029±0.00 0.628±0.26 1.077±0.50 0.168±0.12 0.602±0.02 0.268±0.32 0.513±0.17 0.253±0.00 0.311±0.18 N/A 0.143±0.07

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001614 IMP purinergic nucleotide receptor activity
GO:0002554 IMP serotonin secretion by platelet
GO:0003056 IMP regulation of vascular smooth muscle contraction
GO:0004931 IBA extracellular ATP-gated cation channel activity
GO:0005261 IMP cation channel activity
GO:0005515 IEA protein binding
GO:0005524 IEA ATP binding
GO:0005639 IBA integral component of nuclear inner membrane
GO:0005886 IEA plasma membrane
GO:0006811 IMP ion transport
GO:0006919 IDA activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0006940 IMP regulation of smooth muscle contraction
GO:0007320 IMP insemination
GO:0008144 IEA drug binding
GO:0008217 IEA regulation of blood pressure
GO:0008270 IEA zinc ion binding
GO:0010033 IMP response to organic substance
GO:0019228 IEA neuronal action potential
GO:0019229 IMP regulation of vasoconstriction
GO:0030168 IMP platelet activation
GO:0031240 IDA external side of cell outer membrane
GO:0033198 IMP response to ATP
GO:0035249 IEA synaptic transmission, glutamatergic
GO:0035590 IEA purinergic nucleotide receptor signaling pathway
GO:0042310 IEA vasoconstriction
GO:0043005 IEA neuron projection
GO:0043234 IEA protein complex
GO:0043270 IGI positive regulation of ion transport
GO:0045121 IEA membrane raft
GO:0045211 IDA postsynaptic membrane
GO:0046513 IDA ceramide biosynthetic process
GO:0051260 IEA protein homooligomerization
GO:0051291 IEA protein heterooligomerization
GO:0051924 IMP regulation of calcium ion transport
GO:0098655 IBA cation transmembrane transport

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000016695 p2rx1 purinergic receptor P2X, ligand-gated ion channel, 1 protein_coding Danio_rerio
ENSG00000108405 P2RX1 purinergic receptor P2X, ligand-gated ion channel, 1 protein_coding Homo_sapiens

Loading