C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: mitogen-activated protein kinase kinase kinase 14
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000020941 Map3k14 10090 - 11:103219762-103267472 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000021324 Map3k14-001 103219762-103267472 protein_coding
  ENSMUST00000146163 Map3k14-003 103220805-103221847 processed_transcript
  ENSMUST00000152300 Map3k14-002 103237030-103242271 processed_transcript
  ENSMUST00000152677 Map3k14-004 103239334-103240134 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000021324ENSMUST00000146163ENSMUST00000152300
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000021324 2.020±0.52 1.447±0.57 2.430±0.04 1.345±0.02 3.276±1.54 1.485±0.69 0.931±0.25 1.397±0.26 0.462±0.13 3.961±0.69 1.706±0.22 2.322±0.78 0.746±0.19 1.146±0.42
ENSMUST00000146163 1.388±0.00 3.856±0.56 N/A N/A N/A 2.828±0.00 N/A N/A N/A 3.778±0.00 N/A 3.290±0.00 N/A 2.487±0.36
ENSMUST00000152300 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.521±0.05

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002SG CIL_0002SG_0002 CGP 11:103208127-103267472
CIL_0002S1 CIL_0002S1_0002 CGP 11:103219762-103363692

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000165 IEA MAPK cascade
GO:0000186 IEA activation of MAPKK activity
GO:0004672 ISO protein kinase activity
GO:0004704 IDA NF-kappaB-inducing kinase activity
GO:0004709 IEA MAP kinase kinase kinase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005737 IEA cytoplasm
GO:0006955 IDA immune response
GO:0007249 IDA I-kappaB kinase/NF-kappaB signaling
GO:0038061 IDA NIK/NF-kappaB signaling
GO:0043123 IEA positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0071260 IEA cellular response to mechanical stimulus

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000056582 mitogen-activated protein kinase kinase kinase 14 protein_coding Danio_rerio
ENSDARG00000074060 MAP3K14 mitogen-activated protein kinase kinase kinase 14 protein_coding Danio_rerio
ENSG00000006062 MAP3K14 mitogen-activated protein kinase kinase kinase 14 protein_coding Homo_sapiens

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