C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: proteasome (prosome, macropain) subunit, alpha type 6
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000021024 Psma6 10090 + 12:55384222-55418454 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000021412 Psma6-001 55398775-55418454 protein_coding
  ENSMUST00000162711 Psma6-003 55398795-55418441 nonsense_mediated_decay
  ENSMUST00000162972 Psma6-004 55407383-55412287 processed_transcript
  ENSMUST00000163070 Psma6-002 55384222-55418310 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000021412ENSMUST00000162972ENSMUST00000163070
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000021412 51.475±3.25 19.420±1.13 71.502±3.66 56.479±19.49 35.544±13.61 21.270±1.93 41.615±1.80 41.344±7.50 60.370±21.34 29.032±3.62 71.141±3.55 35.120±19.57 80.950±21.58 74.982±15.13
ENSMUST00000162972 N/A N/A N/A 17.112±0.00 10.410±5.33 11.579±3.88 N/A N/A N/A 6.861±0.00 N/A 14.859±7.85 N/A N/A
ENSMUST00000163070 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 15.259±2.56 16.450±3.10 209.072±49.34

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00045I CIL_00045I_0002 CGP 12:55299577-55418454
CIL_0008MF CIL_0008MF_0002 VISTA 12:55314270-55915258
CIL_0008ME CIL_0008ME_0002 VISTA 12:55343542-55944223
CIL_0001RJ CIL_0001RJ_0002 CGP 12:55384222-55492647

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000502 IEA proteasome complex
GO:0000932 IDA cytoplasmic mRNA processing body
GO:0003723 IDA RNA binding
GO:0004175 IEA endopeptidase activity
GO:0004298 IEA threonine-type endopeptidase activity
GO:0005515 IEA protein binding
GO:0005634 IEA nucleus
GO:0005737 IDA cytoplasm
GO:0005829 TAS cytosol
GO:0005839 IDA proteasome core complex
GO:0005844 ISS polysome
GO:0006511 IEA ubiquitin-dependent protein catabolic process
GO:0007519 NAS skeletal muscle tissue development
GO:0016363 IDA nuclear matrix
GO:0019773 ISS proteasome core complex, alpha-subunit complex
GO:0030016 ISS myofibril
GO:0030017 ISS sarcomere
GO:0051059 IEA NF-kappaB binding
GO:0051092 ISS positive regulation of NF-kappaB transcription factor activity
GO:0051603 ISS proteolysis involved in cellular protein catabolic process
GO:0070062 IEA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000013966 psma6b proteasome (prosome, macropain) subunit, alpha type, 6b protein_coding Danio_rerio
ENSDARG00000019398 psma6a proteasome (prosome, macropain) subunit, alpha type, 6a protein_coding Danio_rerio
ENSG00000100902 PSMA6 proteasome (prosome, macropain) subunit, alpha type, 6 protein_coding Homo_sapiens

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