C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: cathepsin L
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000021477 Ctsl 10090 - 13:64363214-64370306 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000021933 Ctsl-201 64363214-64370306 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000021933
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000021933 153.382±72.22 32.554±3.11 55.949±33.88 13.956±9.11 60.118±15.39 29.718±5.01 40.472±2.49 104.992±45.94 73.681±52.82 37.191±2.76 15.855±10.41 148.059±77.49 205.387±56.31 89.166±15.44

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008Z5 CIL_0008Z5_0002 VISTA 13:63905082-64505639

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004177 ISS aminopeptidase activity
GO:0004197 ISS cysteine-type endopeptidase activity
GO:0005515 IPI protein binding
GO:0005615 IDA extracellular space
GO:0005634 IDA nucleus
GO:0005730 IDA nucleolus
GO:0005737 ISS cytoplasm
GO:0005764 ISS lysosome
GO:0005773 ISS vacuole
GO:0005902 ISS microvillus
GO:0006508 ISS proteolysis
GO:0007154 ISS cell communication
GO:0007283 ISS spermatogenesis
GO:0008584 ISS male gonad development
GO:0009267 ISS cellular response to starvation
GO:0009749 ISS response to glucose
GO:0009897 ISS external side of plasma membrane
GO:0010259 ISS multicellular organismal aging
GO:0010839 IMP negative regulation of keratinocyte proliferation
GO:0014070 ISS response to organic cyclic compound
GO:0016485 IDA protein processing
GO:0016540 IDA protein autoprocessing
GO:0016807 IDA cysteine-type carboxypeptidase activity
GO:0021675 ISS nerve development
GO:0030141 ISS secretory granule
GO:0030984 IEA kininogen binding
GO:0031069 IMP hair follicle morphogenesis
GO:0031410 IDA cytoplasmic vesicle
GO:0032403 IEA protein complex binding
GO:0034698 ISS response to gonadotropin
GO:0042277 ISS peptide binding
GO:0042393 IDA histone binding
GO:0043005 ISS neuron projection
GO:0043204 ISS perikaryon
GO:0045177 ISS apical part of cell
GO:0046697 ISS decidualization
GO:0048102 ISS autophagic cell death
GO:0051384 ISS response to glucocorticoid
GO:0060008 ISS Sertoli cell differentiation
GO:0070062 IEA extracellular vesicular exosome
GO:2000249 IGI regulation of actin cytoskeleton reorganization

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000011701 ctsll cathepsin L, like protein_coding Danio_rerio
ENSDARG00000039173 ctslb cathepsin Lb protein_coding Danio_rerio
ENSDARG00000074306 ctslb cathepsin Lb protein_coding Danio_rerio
ENSDARG00000075527 si:dkey-269i1.3 si:dkey-269i1.3 protein_coding Danio_rerio
ENSDARG00000079376 zgc:174153 zgc:174153 protein_coding Danio_rerio
ENSDARG00000087651 ctslb cathepsin Lb protein_coding Danio_rerio
ENSDARG00000089750 si:dkey-26g8.5 si:dkey-26g8.5 protein_coding Danio_rerio
ENSDARG00000089806 si:dkey-239j18.3 si:dkey-239j18.3 protein_coding Danio_rerio
ENSDARG00000090918 si:dkey-269i1.4 si:dkey-269i1.4 protein_coding Danio_rerio
ENSDARG00000094559 zgc:174855 zgc:174855 protein_coding Danio_rerio
ENSDARG00000095072 si:dkey-26g8.4 si:dkey-26g8.4 protein_coding Danio_rerio
ENSDARG00000095254 si:dkey-239j18.2 si:dkey-239j18.2 protein_coding Danio_rerio
ENSDARG00000095744 si:dkey-269i1.4 si:dkey-269i1.4 protein_coding Danio_rerio
ENSG00000136943 CTSV cathepsin V protein_coding Homo_sapiens

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