C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: SH3-domain binding protein 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000022436 Sh3bp1 10090 + 15:78899667-78919517 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000001226 Sh3bp1-001 78899768-78912047 protein_coding
  ENSMUST00000061239 Sh3bp1-002 78899768-78912051 protein_coding
  ENSMUST00000089378 Sh3bp1-201 78913919-78919517 protein_coding
  ENSMUST00000109698 Sh3bp1-003 78899768-78912051 protein_coding
  ENSMUST00000132047 Sh3bp1-006 78899768-78912051 nonsense_mediated_decay
  ENSMUST00000134703 Sh3bp1-007 78899667-78919032 processed_transcript
  ENSMUST00000148893 Sh3bp1-004 78900428-78902926 protein_coding
  ENSMUST00000151146 Sh3bp1-005 78899768-78912051 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000001226ENSMUST00000061239ENSMUST00000089378ENSMUST00000109698ENSMUST00000151146
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000001226 9.576±4.60 6.356±1.00 10.872±0.44 N/A 31.592±5.77 6.957±1.39 1.715±0.71 4.280±0.70 7.012±6.85 14.068±2.40 0.707±0.58 12.047±5.18 4.520±2.23 0.738±0.12
ENSMUST00000061239 N/A N/A N/A N/A N/A 2.008±0.00 N/A 1.090±0.00 N/A 4.974±0.00 N/A 7.052±1.43 N/A N/A
ENSMUST00000089378 4.476±0.80 8.374±2.58 N/A 49.421±9.84 8.636±1.73 2.011±0.26 0.887±0.09 1.003±0.22 4.371±4.93 N/A 2.053±0.70 8.668±0.38 3.440±1.94 3.369±0.71
ENSMUST00000109698 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.499±0.00 N/A N/A N/A
ENSMUST00000151146 N/A N/A N/A N/A N/A N/A 0.767±0.15 1.240±0.00 N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00099H CIL_00099H_0002 VISTA 15:78863840-79464236
CIL_0008KJ CIL_0008KJ_0002 VISTA 15:78865517-79466323
CIL_0008BX CIL_0008BX_0002 VISTA 15:78873761-79474273
CIL_0008KA CIL_0008KA_0002 VISTA 15:78875821-79476550
CIL_00040D CIL_00040D_0002 CGP 15:78877190-78919517

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000287 IDA magnesium ion binding
GO:0004647 IEA phosphoserine phosphatase activity
GO:0004721 ISS phosphoprotein phosphatase activity
GO:0005515 IPI protein binding
GO:0005737 IEA cytoplasm
GO:0005829 ISS cytosol
GO:0005886 ISS plasma membrane
GO:0005911 IDA cell-cell junction
GO:0006470 ISS protein dephosphorylation
GO:0007088 ISS regulation of mitosis
GO:0007165 IEA signal transduction
GO:0015629 ISS actin cytoskeleton
GO:0017124 IPI SH3 domain binding
GO:0030027 ISS lamellipodium
GO:0030496 ISS midbody
GO:0030836 ISS positive regulation of actin filament depolymerization
GO:0031072 ISO heat shock protein binding
GO:0031247 ISO actin rod assembly
GO:0032154 ISS cleavage furrow
GO:0032361 IDA pyridoxal phosphate catabolic process
GO:0032465 ISS regulation of cytokinesis
GO:0032587 ISS ruffle membrane
GO:0033883 IDA pyridoxal phosphatase activity
GO:0042803 IPI protein homodimerization activity
GO:0070938 ISS contractile ring
GO:0071318 ISO cellular response to ATP

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000078119 sh3bp1 SH3-domain binding protein 1 protein_coding Danio_rerio
ENSG00000100092 SH3BP1 SH3-domain binding protein 1 protein_coding Homo_sapiens

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