C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: excision repair cross-complementing rodent repair deficiency, complementation group 4
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000022545 Ercc4 10090 + 16:13109684-13150617 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000023206 Ercc4-001 13109684-13148734 protein_coding
  ENSMUST00000129049 Ercc4-004 13111794-13150617 nonsense_mediated_decay
  ENSMUST00000138527 Ercc4-002 13109917-13123849 retained_intron
  ENSMUST00000141024 Ercc4-003 13109935-13127630 nonsense_mediated_decay
  ENSMUST00000156393 Ercc4-005 13132391-13144491 processed_transcript

Mus musculus EnsemblGRCm38

Genome
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Genes
Gene structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000023206ENSMUST00000129049
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000023206 4.604±0.16 9.181±1.77 3.936±0.38 5.322±1.11 7.244±1.36 5.580±0.90 2.500±0.22 4.375±1.22 2.012±0.62 5.983±0.64 1.149±0.10 7.991±2.48 3.265±0.81 17.421±4.64
ENSMUST00000129049 0.892±0.00 1.947±0.57 2.143±0.13 1.298±0.39 1.780±0.98 1.089±0.20 0.297±0.00 1.219±0.37 0.331±0.06 1.030±0.00 0.258±0.13 1.234±0.39 0.463±0.12 0.705±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007DX CIL_0007DX_0002 CGP 16:11984113-13150617
CIL_0002RP CIL_0002RP_0003 CGP 16:13109684-13417529

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000014 IBA single-stranded DNA endodeoxyribonuclease activity
GO:0000109 ISO nucleotide-excision repair complex
GO:0000110 IBA nucleotide-excision repair factor 1 complex
GO:0000712 IBA resolution of meiotic recombination intermediates
GO:0000723 IEA telomere maintenance
GO:0000724 IBA double-strand break repair via homologous recombination
GO:0000737 IBA DNA catabolic process, endonucleolytic
GO:0000781 IEA chromosome, telomeric region
GO:0000784 IEA nuclear chromosome, telomeric region
GO:0001094 IDA TFIID-class transcription factor binding
GO:0003684 IBA damaged DNA binding
GO:0003697 IBA single-stranded DNA binding
GO:0004520 IEA endodeoxyribonuclease activity
GO:0005515 IPI protein binding
GO:0005634 IEA nucleus
GO:0005669 IDA transcription factor TFIID complex
GO:0006281 IMP DNA repair
GO:0006289 ISO nucleotide-excision repair
GO:0006295 IEA nucleotide-excision repair, DNA incision, 3'-to lesion
GO:0006296 IBA nucleotide-excision repair, DNA incision, 5'-to lesion
GO:0008022 IEA protein C-terminus binding
GO:0009411 IEA response to UV
GO:0009650 IMP UV protection
GO:0010834 IEA telomere maintenance via telomere shortening
GO:0032205 IEA negative regulation of telomere maintenance
GO:0033683 IEA nucleotide-excision repair, DNA incision
GO:0043566 IEA structure-specific DNA binding
GO:0047485 IEA protein N-terminus binding
GO:1901255 IBA nucleotide-excision repair involved in interstrand cross-link repair

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000014161 ercc4 excision repair cross-complementing rodent repair deficiency, complementation group 4 protein_coding Danio_rerio
ENSG00000175595 ERCC4 excision repair cross-complementation group 4 protein_coding Homo_sapiens

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