C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: histidine-rich glycoprotein
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000022877 Hrg 10090 + 16:22951072-22961656 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000023590 Hrg-001 22951072-22961656 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaENSMUST00000023590
Transcript ID Adipose Adrenal Bladder Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta
ENSMUST00000023590 0.078±0.02 0.238±0.13 0.010±0.00 0.498±0.08 0.111±0.00 0.061±0.02 0.053±0.04 94.122±87.78 0.052±0.03 0.093±0.07 0.114±0.10 0.014±0.01

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008PR CIL_0008PR_0002 VISTA 16:22397940-22999797
CIL_000044 CIL_000044_0002 CGP 16:22918382-22961656
CIL_0008LA CIL_0008LA_0002 VISTA 16:22937415-23544553
CIL_000043 CIL_000043_0002 CGP 16:22951072-23029101

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001525 IEA angiogenesis
GO:0002839 IMP positive regulation of immune response to tumor cell
GO:0004867 IMP serine-type endopeptidase inhibitor activity
GO:0004869 IEA cysteine-type endopeptidase inhibitor activity
GO:0005102 ISS receptor binding
GO:0005515 IPI protein binding
GO:0006935 IEA chemotaxis
GO:0007162 ISS negative regulation of cell adhesion
GO:0008201 ISS heparin binding
GO:0008270 ISS zinc ion binding
GO:0008285 ISS negative regulation of cell proliferation
GO:0010468 IMP regulation of gene expression
GO:0010543 IMP regulation of platelet activation
GO:0010593 ISS negative regulation of lamellipodium assembly
GO:0010951 IEA negative regulation of endopeptidase activity
GO:0014070 IDA response to organic cyclic compound
GO:0015886 IMP heme transport
GO:0016525 IMP negative regulation of angiogenesis
GO:0019865 ISS immunoglobulin binding
GO:0020037 ISS heme binding
GO:0030168 ISS platelet activation
GO:0030193 IMP regulation of blood coagulation
GO:0030308 IDA negative regulation of cell growth
GO:0031982 IDA vesicle
GO:0032956 ISS regulation of actin cytoskeleton organization
GO:0033629 ISS negative regulation of cell adhesion mediated by integrin
GO:0034395 IDA regulation of transcription from RNA polymerase II promoter in response to iron
GO:0036019 IDA endolysosome
GO:0042730 IEA fibrinolysis
GO:0043065 ISS positive regulation of apoptotic process
GO:0043254 ISS regulation of protein complex assembly
GO:0043395 ISS heparan sulfate proteoglycan binding
GO:0043537 IMP negative regulation of blood vessel endothelial cell migration
GO:0046872 ISS metal ion binding
GO:0050730 ISS regulation of peptidyl-tyrosine phosphorylation
GO:0050832 IMP defense response to fungus
GO:0051894 ISS positive regulation of focal adhesion assembly
GO:0051918 IMP negative regulation of fibrinolysis
GO:0061474 IDA phagolysosome membrane
GO:0070062 IEA extracellular vesicular exosome
GO:0072562 IEA blood microparticle
GO:0097037 IMP heme export
GO:1900747 ISS negative regulation of vascular endothelial growth factor signaling pathway
GO:2000504 IMP positive regulation of blood vessel remodeling
GO:2001027 ISS negative regulation of endothelial cell chemotaxis

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000113905 HRG histidine-rich glycoprotein protein_coding Homo_sapiens

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