C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: adiponectin, C1Q and collagen domain containing
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000022878 Adipoq 10090 + 16:23146536-23158028 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000023593 Adipoq-001 23146536-23158028 protein_coding
  ENSMUST00000171309 Adipoq-002 23146646-23157292 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaENSMUST00000023593ENSMUST00000171309
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta
ENSMUST00000023593 1334.612±826.74 172.560±54.52 22.288±11.62 0.028±0.00 611.884±180.72 12.665±1.82 16.207±8.38 32.533±13.80 0.013±0.01 26.372±16.35 5.389±5.63 103.517±57.88 18.115±18.07
ENSMUST00000171309 N/A N/A N/A 0.011±0.00 N/A N/A N/A N/A 0.120±0.07 N/A N/A N/A 0.169±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008LA CIL_0008LA_0002 VISTA 16:22937415-23544553
CIL_000048 CIL_000048_0002 CGP 16:23113943-23158028

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001666 IEA response to hypoxia
GO:0001934 ISS positive regulation of protein phosphorylation
GO:0005102 IDA receptor binding
GO:0005179 TAS hormone activity
GO:0005515 IPI protein binding
GO:0005581 IEA collagen trimer
GO:0005615 IDA extracellular space
GO:0005783 IDA endoplasmic reticulum
GO:0006006 IDA glucose metabolic process
GO:0006635 IMP fatty acid beta-oxidation
GO:0007584 IEA response to nutrient
GO:0007623 IEA circadian rhythm
GO:0009744 IEA response to sucrose
GO:0009749 IMP response to glucose
GO:0009967 IDA positive regulation of signal transduction
GO:0009986 ISS cell surface
GO:0010642 IDA negative regulation of platelet-derived growth factor receptor signaling pathway
GO:0010739 ISS positive regulation of protein kinase A signaling
GO:0010745 ISS negative regulation of macrophage derived foam cell differentiation
GO:0010804 ISS negative regulation of tumor necrosis factor-mediated signaling pathway
GO:0010875 ISS positive regulation of cholesterol efflux
GO:0010906 ISS regulation of glucose metabolic process
GO:0014823 IEA response to activity
GO:0014912 ISS negative regulation of smooth muscle cell migration
GO:0019395 IDA fatty acid oxidation
GO:0030336 IDA negative regulation of cell migration
GO:0030853 ISS negative regulation of granulocyte differentiation
GO:0031667 IEA response to nutrient levels
GO:0031953 ISS negative regulation of protein autophosphorylation
GO:0032270 ISS positive regulation of cellular protein metabolic process
GO:0032720 ISS negative regulation of tumor necrosis factor production
GO:0032757 ISS positive regulation of interleukin-8 production
GO:0032869 IGI cellular response to insulin stimulus
GO:0033034 ISS positive regulation of myeloid cell apoptotic process
GO:0033211 IEA adiponectin-activated signaling pathway
GO:0033691 IEA sialic acid binding
GO:0034115 ISS negative regulation of heterotypic cell-cell adhesion
GO:0034383 ISS low-density lipoprotein particle clearance
GO:0034612 ISS response to tumor necrosis factor
GO:0035690 IDA cellular response to drug
GO:0042493 IEA response to drug
GO:0042593 IDA glucose homeostasis
GO:0042802 IPI identical protein binding
GO:0042803 IEA protein homodimerization activity
GO:0043123 IDA positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043124 ISS negative regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043407 IDA negative regulation of MAP kinase activity
GO:0045471 IEA response to ethanol
GO:0045599 IDA negative regulation of fat cell differentiation
GO:0045650 ISS negative regulation of macrophage differentiation
GO:0045715 ISS negative regulation of low-density lipoprotein particle receptor biosynthetic process
GO:0045721 IDA negative regulation of gluconeogenesis
GO:0045776 ISS negative regulation of blood pressure
GO:0045777 IEA positive regulation of blood pressure
GO:0045860 IEA positive regulation of protein kinase activity
GO:0045892 IMP negative regulation of transcription, DNA-templated
GO:0045923 IMP positive regulation of fatty acid metabolic process
GO:0046326 IDA positive regulation of glucose import
GO:0046888 IEA negative regulation of hormone secretion
GO:0048471 ISS perinuclear region of cytoplasm
GO:0048662 ISS negative regulation of smooth muscle cell proliferation
GO:0050728 IDA negative regulation of inflammatory response
GO:0050731 IEA positive regulation of peptidyl-tyrosine phosphorylation
GO:0050765 ISS negative regulation of phagocytosis
GO:0050805 ISS negative regulation of synaptic transmission
GO:0050873 IDA brown fat cell differentiation
GO:0051260 IDA protein homooligomerization
GO:0051384 IEA response to glucocorticoid
GO:0051899 IEA membrane depolarization
GO:0060081 IEA membrane hyperpolarization
GO:0070062 IEA extracellular vesicular exosome
GO:0070208 IPI protein heterotrimerization
GO:0070373 ISS negative regulation of ERK1 and ERK2 cascade
GO:0070543 IEA response to linoleic acid
GO:0070994 IMP detection of oxidative stress
GO:0071320 IEA cellular response to cAMP
GO:0071639 ISS positive regulation of monocyte chemotactic protein-1 production
GO:0071872 IEA cellular response to epinephrine stimulus
GO:0071944 ISS cell periphery
GO:0072659 ISS protein localization to plasma membrane
GO:0090317 ISS negative regulation of intracellular protein transport
GO:1900121 ISS negative regulation of receptor binding
GO:2000279 ISS negative regulation of DNA biosynthetic process
GO:2000467 ISS positive regulation of glycogen (starch) synthase activity
GO:2000478 IMP positive regulation of metanephric glomerular visceral epithelial cell development
GO:2000481 IMP positive regulation of cAMP-dependent protein kinase activity
GO:2000534 IMP positive regulation of renal albumin absorption
GO:2000584 IDA negative regulation of platelet-derived growth factor receptor-alpha signaling pathway
GO:2000590 IDA negative regulation of metanephric mesenchymal cell migration

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000056411 adipoqb adiponectin, C1Q and collagen domain containing, b protein_coding Danio_rerio
ENSDARG00000062228 adipoqa adiponectin, C1Q and collagen domain containing, a protein_coding Danio_rerio
ENSG00000181092 ADIPOQ adiponectin, C1Q and collagen domain containing protein_coding Homo_sapiens

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