C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: runt related transcription factor 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000022952 Runx1 10090 - 16:92601466-92826149 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000023673 Runx1-001 92601466-92826149 protein_coding
  ENSMUST00000113956 Runx1-003 92603656-92697328 protein_coding
  ENSMUST00000168195 Runx1-004 92605398-92696125 protein_coding
  ENSMUST00000186296 Runx1-002 92695592-92825778 protein_coding
  ENSMUST00000187242 Runx1-007 92686956-92695495 protein_coding
  ENSMUST00000189126 Runx1-005 92686989-92697325 retained_intron
  ENSMUST00000189679 Runx1-006 92815428-92826074 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000023673ENSMUST00000113956ENSMUST00000168195ENSMUST00000187242ENSMUST00000189126ENSMUST00000189679
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000023673 0.693±0.13 0.200±0.05 N/A 0.033±0.00 2.238±0.91 0.795±0.20 0.112±0.06 0.104±0.02 0.479±0.48 2.806±0.42 0.118±0.04 1.130±0.28 0.143±0.05 0.035±0.02
ENSMUST00000113956 0.578±0.26 0.591±0.17 0.903±0.00 N/A 4.449±0.20 1.042±0.22 0.089±0.01 0.125±0.00 0.036±0.01 2.742±1.04 0.060±0.01 3.982±1.35 0.221±0.02 0.057±0.02
ENSMUST00000168195 0.643±0.13 0.696±0.17 N/A 0.176±0.07 7.763±3.60 2.194±0.60 0.311±0.20 0.328±0.14 0.821±0.90 4.350±0.96 0.182±0.00 5.533±1.53 0.814±0.48 0.108±0.05
ENSMUST00000187242 N/A N/A N/A N/A N/A N/A N/A N/A 0.212±0.00 N/A N/A N/A N/A N/A
ENSMUST00000189126 N/A N/A N/A 0.014±0.00 N/A N/A 0.060±0.00 N/A 0.023±0.00 N/A N/A N/A N/A 0.062±0.01
ENSMUST00000189679 N/A N/A N/A N/A N/A N/A N/A N/A 0.057±0.00 N/A N/A N/A N/A 0.049±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008ON CIL_0008ON_0002 VISTA 16:92040534-92642015
CIL_0007SX CIL_0007SX_0002 VISTA 16:92042784-92648394
CIL_0008OM CIL_0008OM_0002 VISTA 16:92044467-92645647
CIL_0008ZS CIL_0008ZS_0002 VISTA 16:92110151-92716672
CIL_00094R CIL_00094R_0002 VISTA 16:92127453-92730131
CIL_00078F CIL_00078F_0002 CGP 16:92485736-92826149

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000975 IEA regulatory region DNA binding
GO:0001501 IMP skeletal system development
GO:0001701 IMP in utero embryonic development
GO:0001889 IMP liver development
GO:0002318 IMP myeloid progenitor cell differentiation
GO:0003677 IDA DNA binding
GO:0003700 IDA sequence-specific DNA binding transcription factor activity
GO:0005509 IEA calcium ion binding
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005604 IDA basement membrane
GO:0005634 IDA nucleus
GO:0006355 IDA regulation of transcription, DNA-templated
GO:0007417 IMP central nervous system development
GO:0008134 IEA transcription factor binding
GO:0009966 IMP regulation of signal transduction
GO:0030099 IEA myeloid cell differentiation
GO:0030182 IMP neuron differentiation
GO:0030853 IEA negative regulation of granulocyte differentiation
GO:0030854 IEA positive regulation of granulocyte differentiation
GO:0031069 IMP hair follicle morphogenesis
GO:0035162 IMP embryonic hemopoiesis
GO:0042803 IEA protein homodimerization activity
GO:0045893 IEA positive regulation of transcription, DNA-templated
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0046982 IEA protein heterodimerization activity
GO:0048266 IMP behavioral response to pain
GO:0048666 IMP neuron development
GO:0060216 IMP definitive hemopoiesis
GO:0070491 IPI repressing transcription factor binding
GO:0071336 IMP regulation of hair follicle cell proliferation
GO:0071560 IDA cellular response to transforming growth factor beta stimulus
GO:2000872 IEA positive regulation of progesterone secretion

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000025921 runx1 runt-related transcription factor 1 protein_coding Danio_rerio
ENSDARG00000087646 RUNX1 (2 of 2) runt-related transcription factor 1 protein_coding Danio_rerio
ENSG00000159216 RUNX1 runt-related transcription factor 1 protein_coding Homo_sapiens

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