C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: axin 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000024182 Axin1 10090 + 17:26138688-26195811 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000074370 Axin1-001 26138688-26195811 protein_coding
  ENSMUST00000118904 Axin1-201 26138828-26195241 protein_coding
  ENSMUST00000163421 Axin1-002 26138950-26195294 protein_coding
  ENSMUST00000168282 Axin1-004 26143347-26184314 protein_coding
  ENSMUST00000169268 Axin1-005 26188153-26188795 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000074370ENSMUST00000118904ENSMUST00000163421ENSMUST00000169268
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000074370 5.387±1.94 3.983±2.55 5.553±0.31 5.261±1.56 4.734±1.91 6.589±1.73 2.751±0.04 4.114±1.82 3.303±1.86 7.114±1.07 2.635±0.64 9.889±2.12 10.509±5.06 3.792±1.26
ENSMUST00000118904 2.001±0.00 2.450±0.17 N/A 5.390±0.00 2.918±0.00 2.402±0.00 N/A N/A 1.775±0.56 2.905±0.00 1.745±0.68 7.866±3.74 11.225±3.12 6.108±0.00
ENSMUST00000163421 1.883±0.60 N/A 4.532±0.19 5.836±1.65 1.734±0.00 1.822±0.22 1.037±0.17 1.815±0.29 2.673±1.83 N/A 1.836±0.88 3.145±0.60 4.603±0.39 2.117±0.37
ENSMUST00000169268 N/A N/A N/A 81.514±0.00 N/A N/A N/A N/A N/A N/A N/A 218.248±0.00 184.851±8.01 181.253±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000209 IDA protein polyubiquitination
GO:0001701 IGI in utero embryonic development
GO:0001743 IBA optic placode formation
GO:0001932 IGI regulation of protein phosphorylation
GO:0001934 IDA positive regulation of protein phosphorylation
GO:0002039 IPI p53 binding
GO:0004871 IEA signal transducer activity
GO:0005096 IBA GTPase activator activity
GO:0005102 IEA receptor binding
GO:0005515 IPI protein binding
GO:0005634 IEA nucleus
GO:0005737 ISO cytoplasm
GO:0005794 IEA Golgi apparatus
GO:0005881 IDA cytoplasmic microtubule
GO:0005886 IDA plasma membrane
GO:0005938 IDA cell cortex
GO:0006913 IDA nucleocytoplasmic transport
GO:0006915 IEA apoptotic process
GO:0007257 IBA activation of JUN kinase activity
GO:0007368 IBA determination of left/right symmetry
GO:0007605 IMP sensory perception of sound
GO:0008013 IPI beta-catenin binding
GO:0008022 IDA protein C-terminus binding
GO:0008219 IBA cell death
GO:0009950 IDA dorsal/ventral axis specification
GO:0009953 ISO dorsal/ventral pattern formation
GO:0014069 IBA postsynaptic density
GO:0016023 IDA cytoplasmic membrane-bounded vesicle
GO:0016055 IDA Wnt signaling pathway
GO:0016328 IEA lateral plasma membrane
GO:0019899 IEA enzyme binding
GO:0019901 IPI protein kinase binding
GO:0019904 IPI protein domain specific binding
GO:0021797 IBA forebrain anterior/posterior pattern specification
GO:0021881 IBA Wnt-activated signaling pathway involved in forebrain neuron fate commitment
GO:0030163 IDA protein catabolic process
GO:0030178 IDA negative regulation of Wnt signaling pathway
GO:0030511 IDA positive regulation of transforming growth factor beta receptor signaling pathway
GO:0030877 IDA beta-catenin destruction complex
GO:0030910 IBA olfactory placode formation
GO:0031122 IGI cytoplasmic microtubule organization
GO:0031398 IDA positive regulation of protein ubiquitination
GO:0031410 IEA cytoplasmic vesicle
GO:0031625 IPI ubiquitin protein ligase binding
GO:0032147 IEA activation of protein kinase activity
GO:0032436 IDA positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0032947 IMP protein complex scaffold
GO:0034244 IDA negative regulation of transcription elongation from RNA polymerase II promoter
GO:0035412 IDA regulation of catenin import into nucleus
GO:0036342 IMP post-anal tail morphogenesis
GO:0038032 IEA termination of G-protein coupled receptor signaling pathway
GO:0042802 IPI identical protein binding
GO:0042803 IPI protein homodimerization activity
GO:0043234 IDA protein complex
GO:0043507 IDA positive regulation of JUN kinase activity
GO:0043547 IBA positive regulation of GTPase activity
GO:0043621 IPI protein self-association
GO:0043623 IEA cellular protein complex assembly
GO:0045599 IDA negative regulation of fat cell differentiation
GO:0045860 IEA positive regulation of protein kinase activity
GO:0045893 IDA positive regulation of transcription, DNA-templated
GO:0046330 IMP positive regulation of JNK cascade
GO:0046332 IEA SMAD binding
GO:0048048 IBA embryonic eye morphogenesis
GO:0048318 IMP axial mesoderm development
GO:0048320 IMP axial mesoderm formation
GO:0048471 IEA perinuclear region of cytoplasm
GO:0051248 IDA negative regulation of protein metabolic process
GO:0051260 IDA protein homooligomerization
GO:0051443 IMP positive regulation of ubiquitin-protein transferase activity
GO:0055001 IBA muscle cell development
GO:0060070 IDA canonical Wnt signaling pathway
GO:0060823 IBA canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation
GO:0070016 IBA armadillo repeat domain binding
GO:0070411 IPI:IDA I-SMAD binding
GO:0070412 IPI R-SMAD binding
GO:0071407 IBA cellular response to organic cyclic compound
GO:0071514 IMP genetic imprinting
GO:0071944 IEA cell periphery
GO:0090090 IDA negative regulation of canonical Wnt signaling pathway
GO:0090244 IBA Wnt signaling pathway involved in somitogenesis
GO:2000060 IDA positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000026534 axin1 axin 1 protein_coding Danio_rerio
ENSG00000103126 AXIN1 axin 1 protein_coding Homo_sapiens

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