C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: SAM pointed domain containing ets transcription factor
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000024215 Spdef 10090 - 17:27714352-27728951 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000025054 Spdef-201 27714447-27728951 protein_coding
  ENSMUST00000114870 Spdef-001 27714352-27728950 protein_coding
  ENSMUST00000127622 Spdef-003 27714505-27717582 processed_transcript
  ENSMUST00000138970 Spdef-002 27719992-27728924 protein_coding
  ENSMUST00000167489 Spdef-202 27714449-27728889 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000025054ENSMUST00000114870ENSMUST00000127622ENSMUST00000138970ENSMUST00000167489
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000025054 0.363±0.03 0.083±0.00 0.086±0.00 N/A 2.845±1.27 88.767±38.78 0.056±0.00 0.034±0.01 0.065±0.05 1.724±0.32 N/A 5.621±2.55 0.153±0.06 N/A
ENSMUST00000114870 N/A 0.057±0.00 N/A 0.246±0.00 N/A N/A N/A N/A N/A N/A N/A N/A 0.104±0.05 0.141±0.00
ENSMUST00000127622 N/A 0.084±0.06 N/A 0.334±0.00 1.641±0.00 N/A 0.010±0.00 0.124±0.10 0.046±0.03 N/A 0.118±0.03 1.909±0.83 0.627±0.35 1.174±0.52
ENSMUST00000138970 0.039±0.00 0.034±0.00 N/A N/A N/A N/A 0.046±0.00 N/A 0.032±0.02 N/A 0.123±0.00 N/A 0.227±0.00 N/A
ENSMUST00000167489 N/A 0.058±0.04 N/A 0.148±0.00 1.373±0.00 N/A 0.042±0.01 0.027±0.00 0.038±0.02 N/A 0.020±0.00 1.078±0.51 0.150±0.00 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004LR CIL_0004LR_0003 CGP 17:27655509-27728951
CIL_0004LT CIL_0004LT_0003 CGP 17:27714352-27820558

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IMP negative regulation of transcription from RNA polymerase II promoter
GO:0000981 IBA sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0005634 IDA nucleus
GO:0006366 IBA transcription from RNA polymerase II promoter
GO:0010454 IMP negative regulation of cell fate commitment
GO:0010455 IMP positive regulation of cell fate commitment
GO:0043065 IEA positive regulation of apoptotic process
GO:0043565 IEA sequence-specific DNA binding
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0060480 IDA lung goblet cell differentiation
GO:0060576 IMP intestinal epithelial cell development

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000029930 SPDEF SAM pointed domain containing ETS transcription factor protein_coding Danio_rerio
ENSG00000124664 SPDEF SAM pointed domain containing ETS transcription factor protein_coding Homo_sapiens

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