C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: complement component 2 (within H-2S)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000024371 C2 10090 - 17:34862604-34898265 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000025230 C2-001 34862605-34882100 protein_coding
  ENSMUST00000127795 C2-005 34864169-34864952 retained_intron
  ENSMUST00000130728 C2-006 34877054-34881967 processed_transcript
  ENSMUST00000134300 C2-003 34863672-34864412 protein_coding
  ENSMUST00000148431 C2-004 34862606-34895547 protein_coding
  ENSMUST00000152417 C2-002 34862604-34882026 protein_coding
  ENSMUST00000174279 C2-010 34893353-34898265 processed_transcript
  ENSMUST00000174880 C2-009 34893350-34895557 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000025230ENSMUST00000152417
Transcript ID Adipose Adrenal Bladder Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000025230 29.547±1.97 53.934±3.76 31.422±8.99 25.358±5.31 2.789±0.26 2.082±0.26 33.064±3.22 28.654±15.18 15.280±1.90 0.752±0.20 26.800±2.58 9.737±7.73 5.631±1.95
ENSMUST00000152417 N/A N/A N/A 18.204±0.00 N/A N/A N/A N/A N/A 1.128±0.00 20.368±4.94 0.663±0.00 2.600±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001PM CIL_0001PM_0004 CGP 17:34856374-34882042
CIL_000421 CIL_000421_0002 CGP 17:34862604-34898265

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004252 IEA serine-type endopeptidase activity
GO:0005515 IEA protein binding
GO:0005576 IEA extracellular region
GO:0006508 IEA proteolysis
GO:0006956 IEA complement activation
GO:0006958 IEA complement activation, classical pathway
GO:0007584 IEA response to nutrient
GO:0045087 IEA innate immune response
GO:0046872 IEA metal ion binding
GO:0070062 IEA extracellular vesicular exosome
GO:2000427 IEA positive regulation of apoptotic cell clearance

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000019772 complement component 2 protein_coding Danio_rerio
ENSG00000166278 C2 complement component 2 protein_coding Homo_sapiens

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