C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: BCL2-associated athanogene 6
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000024392 Bag6 10090 + 17:35135178-35147322 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000025250 Bag6-201 35135178-35147322 protein_coding
  ENSMUST00000166426 Bag6-001 35135178-35147305 protein_coding
  ENSMUST00000172571 Bag6-002 35135205-35147306 protein_coding
  ENSMUST00000172882 Bag6-010 35146377-35147296 retained_intron
  ENSMUST00000172889 Bag6-007 35136123-35138965 retained_intron
  ENSMUST00000172925 Bag6-006 35138573-35139850 retained_intron
  ENSMUST00000172993 Bag6-017 35145888-35147319 protein_coding
  ENSMUST00000173351 Bag6-011 35140231-35141393 retained_intron
  ENSMUST00000173491 Bag6-015 35135228-35140309 protein_coding
  ENSMUST00000173535 Bag6-003 35135486-35142595 protein_coding
  ENSMUST00000173550 Bag6-004 35135744-35147320 protein_coding
  ENSMUST00000173952 Bag6-014 35135510-35140372 protein_coding
  ENSMUST00000174281 Bag6-005 35135730-35146349 protein_coding
  ENSMUST00000174478 Bag6-009 35135718-35138705 protein_coding
  ENSMUST00000174613 Bag6-013 35141977-35142602 retained_intron
  ENSMUST00000174797 Bag6-008 35141159-35141986 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000025250ENSMUST00000166426ENSMUST00000172571ENSMUST00000173491ENSMUST00000173535ENSMUST00000173550ENSMUST00000174281
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000025250 21.932±2.28 50.482±8.29 21.341±2.14 23.950±6.52 20.840±3.90 21.284±7.39 16.927±4.50 19.405±3.57 11.606±3.06 17.523±5.02 27.771±1.01 32.780±7.40 15.873±2.71 173.488±76.46
ENSMUST00000166426 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 6.382±0.00 15.872±0.00
ENSMUST00000172571 N/A N/A N/A N/A N/A N/A N/A N/A N/A 10.506±0.00 N/A N/A N/A N/A
ENSMUST00000173491 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 88.115±0.00
ENSMUST00000173535 15.667±0.88 N/A 15.246±0.47 39.657±0.00 N/A 20.340±0.00 10.701±0.00 11.671±2.11 11.199±3.52 19.395±1.86 N/A 36.243±3.24 17.051±7.52 N/A
ENSMUST00000173550 10.451±1.51 N/A 9.652±3.07 18.355±2.25 9.361±0.00 11.276±2.55 6.729±1.52 6.640±1.01 6.546±2.52 12.681±0.96 14.940±1.23 15.636±2.21 12.859±5.67 N/A
ENSMUST00000174281 11.098±2.27 53.078±10.93 N/A 16.963±0.00 18.432±8.41 24.388±2.26 5.355±0.65 6.334±1.88 5.146±1.31 13.276±4.88 N/A 35.461±16.50 7.039±2.78 56.166±17.79

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001822 IMP kidney development
GO:0002474 TAS antigen processing and presentation of peptide antigen via MHC class I
GO:0005515 IPI protein binding
GO:0005634 IDA:ISS nucleus
GO:0005737 ISS cytoplasm
GO:0005829 ISS cytosol
GO:0006511 IMP ubiquitin-dependent protein catabolic process
GO:0006810 IEA transport
GO:0006915 RCA apoptotic process
GO:0007130 IMP synaptonemal complex assembly
GO:0007283 IMP spermatogenesis
GO:0007420 IMP brain development
GO:0009790 IMP embryo development
GO:0016568 IEA chromatin modification
GO:0018393 ISS internal peptidyl-lysine acetylation
GO:0030154 IEA cell differentiation
GO:0030324 IMP lung development
GO:0030544 IPI Hsp70 protein binding
GO:0031593 IDA polyubiquitin binding
GO:0031625 IEA ubiquitin protein ligase binding
GO:0032435 IMP negative regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0042127 IEA regulation of cell proliferation
GO:0042771 ISS intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
GO:0042981 RCA regulation of apoptotic process
GO:0043022 ISS ribosome binding
GO:0043066 IGI negative regulation of apoptotic process
GO:0045861 IMP negative regulation of proteolysis
GO:0050821 IMP protein stabilization
GO:0070059 IMP intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
GO:0070628 IDA proteasome binding
GO:0071816 ISS tail-anchored membrane protein insertion into ER membrane
GO:0071818 ISS BAT3 complex

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000075892 bag6 BCL2-associated athanogene 6 protein_coding Danio_rerio
ENSDARG00000077531 BAG6 (2 of 2) BCL2-associated athanogene 6 protein_coding Danio_rerio
ENSG00000204463 BAG6 BCL2-associated athanogene 6 protein_coding Homo_sapiens

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