C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: aldehyde dehydrogenase 18 family, member A1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000025007 Aldh18a1 10090 - 19:40550257-40588463 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000025979 Aldh18a1-001 40550257-40588463 protein_coding
  ENSMUST00000134749 Aldh18a1-002 40557057-40588423 retained_intron
  ENSMUST00000149476 Aldh18a1-003 40577615-40588410 protein_coding
  ENSMUST00000155613 Aldh18a1-004 40551151-40554863 retained_intron
  ENSMUST00000175932 Aldh18a1-005 40577658-40588382 protein_coding
  ENSMUST00000175967 Aldh18a1-008 40553427-40554741 protein_coding
  ENSMUST00000176939 Aldh18a1-007 40550257-40588369 protein_coding
  ENSMUST00000176955 Aldh18a1-006 40574344-40588384 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000025979ENSMUST00000134749ENSMUST00000149476ENSMUST00000155613ENSMUST00000176939
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000025979 9.605±7.16 3.552±1.51 18.713±2.89 19.149±0.59 3.909±1.34 3.927±1.62 2.383±0.61 0.842±0.48 12.057±6.65 3.407±0.36 0.822±0.26 13.076±3.29 18.368±11.72 1.116±0.63
ENSMUST00000134749 N/A 2.882±0.26 N/A 1.096±0.00 1.529±0.00 2.252±0.00 N/A 0.414±0.11 0.203±0.00 N/A N/A 7.143±0.99 N/A N/A
ENSMUST00000149476 N/A 5.648±1.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENSMUST00000155613 N/A N/A N/A N/A N/A N/A N/A N/A 0.364±0.00 N/A N/A N/A N/A N/A
ENSMUST00000176939 4.029±2.89 3.043±1.75 7.333±3.28 4.475±2.14 4.179±1.08 10.223±0.42 1.177±0.43 1.234±0.50 2.569±2.68 1.377±0.38 0.597±0.35 13.958±5.73 7.902±3.11 0.740±0.38

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00095J CIL_00095J_0002 VISTA 19:40075645-40678667
CIL_0007T2 CIL_0007T2_0002 VISTA 19:40167411-40768695
CIL_00067I CIL_00067I_0002 CGP 19:40295049-40588463
CIL_00067D CIL_00067D_0002 CGP 19:40550257-40612233

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004349 IDA glutamate 5-kinase activity
GO:0004350 ISS glutamate-5-semialdehyde dehydrogenase activity
GO:0005524 IEA ATP binding
GO:0005737 IEA cytoplasm
GO:0005739 IDA mitochondrion
GO:0005743 IEA mitochondrial inner membrane
GO:0006536 ISS glutamate metabolic process
GO:0006561 ISS proline biosynthetic process
GO:0006592 IEA ornithine biosynthetic process
GO:0008652 TAS cellular amino acid biosynthetic process
GO:0016310 IDA:IEA phosphorylation
GO:0019240 ISS citrulline biosynthetic process
GO:0044822 IEA poly(A) RNA binding
GO:0055114 IEA oxidation-reduction process
GO:0055129 IEA L-proline biosynthetic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000061123 aldh18a1 aldehyde dehydrogenase 18 family, member A1 protein_coding Danio_rerio
ENSG00000059573 ALDH18A1 aldehyde dehydrogenase 18 family, member A1 protein_coding Homo_sapiens

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