C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: HECT, UBA and WWE domain containing 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000025261 Huwe1 10090 + X:151800807-151935417 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000026292 Huwe1-002 151803327-151935417 protein_coding
  ENSMUST00000112622 Huwe1-001 151835248-151935417 protein_coding
  ENSMUST00000123306 Huwe1-019 151864562-151873902 nonsense_mediated_decay
  ENSMUST00000129714 Huwe1-011 151800807-151802263 processed_transcript
  ENSMUST00000130234 Huwe1-023 151921343-151923733 retained_intron
  ENSMUST00000130243 Huwe1-004 151803347-151873548 retained_intron
  ENSMUST00000131786 Huwe1-006 151803347-151860546 retained_intron
  ENSMUST00000132453 Huwe1-020 151908845-151910192 retained_intron
  ENSMUST00000133051 Huwe1-022 151921282-151922612 retained_intron
  ENSMUST00000137816 Huwe1-015 151803327-151853201 retained_intron
  ENSMUST00000138023 Huwe1-016 151860167-151891151 nonsense_mediated_decay
  ENSMUST00000138566 Huwe1-014 151803662-151840108 nonsense_mediated_decay
  ENSMUST00000139245 Huwe1-017 151924258-151927747 retained_intron
  ENSMUST00000139386 Huwe1-010 151800883-151804511 processed_transcript
  ENSMUST00000139909 Huwe1-021 151908845-151910389 retained_intron
  ENSMUST00000147666 Huwe1-008 151803662-151847589 processed_transcript
  ENSMUST00000149344 Huwe1-007 151803261-151806860 processed_transcript
  ENSMUST00000150020 Huwe1-005 151803662-151872198 retained_intron
  ENSMUST00000150426 Huwe1-018 151904994-151909917 retained_intron
  ENSMUST00000150882 Huwe1-024 151882586-151883300 processed_transcript
  ENSMUST00000152757 Huwe1-009 151801314-151806860 processed_transcript
  ENSMUST00000153687 Huwe1-003 151803243-151873033 nonsense_mediated_decay
  ENSMUST00000156616 Huwe1-013 151803658-151835276 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000026292ENSMUST00000112622
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000026292 2.223±0.00 3.506±0.00 4.785±0.39 7.798±3.64 3.303±0.33 2.459±0.09 4.110±0.43 3.342±1.38 1.963±0.72 5.030±0.40 3.882±1.87 9.254±5.07 8.776±3.43 2.282±0.08
ENSMUST00000112622 8.602±2.53 4.001±0.83 3.961±0.00 7.687±0.92 14.776±2.92 5.988±3.11 5.784±2.43 5.531±1.67 3.184±1.53 9.728±3.06 3.862±1.36 16.734±6.99 12.542±8.43 2.201±0.73

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000209 IEA protein polyubiquitination
GO:0003677 ISS DNA binding
GO:0004842 IBA ubiquitin-protein transferase activity
GO:0005634 IBA nucleus
GO:0005737 IBA cytoplasm
GO:0006284 IEA base-excision repair
GO:0006513 IEA protein monoubiquitination
GO:0016020 IEA membrane
GO:0016574 IEA histone ubiquitination
GO:0016874 IEA ligase activity
GO:0030154 IEA cell differentiation
GO:0042787 IBA protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0044822 IEA poly(A) RNA binding
GO:0070062 IEA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000016782 huwe1 HECT, UBA and WWE domain containing 1 protein_coding Danio_rerio
ENSG00000086758 HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase protein_coding Homo_sapiens

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