C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: interferon regulatory factor 7
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000025498 Irf7 10090 - 7:141262706-141266481 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000026571 Irf7-001 141263183-141266481 protein_coding
  ENSMUST00000097952 Irf7-002 141263184-141266423 protein_coding
  ENSMUST00000106023 Irf7-003 141262706-141266421 protein_coding
  ENSMUST00000123525 Irf7-011 141263432-141265292 protein_coding
  ENSMUST00000127161 Irf7-008 141265215-141265984 retained_intron
  ENSMUST00000127223 Irf7-012 141263791-141265131 retained_intron
  ENSMUST00000131399 Irf7-007 141263973-141266044 processed_transcript
  ENSMUST00000146373 Irf7-006 141265376-141266421 processed_transcript
  ENSMUST00000148414 Irf7-010 141264223-141265473 retained_intron
  ENSMUST00000155744 Irf7-004 141263187-141266422 retained_intron
  ENSMUST00000156938 Irf7-009 141264800-141265707 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBreastColonHeartKidneyLiverLungOvaryPlacentaENSMUST00000026571ENSMUST00000097952ENSMUST00000106023ENSMUST00000131399ENSMUST00000155744
Transcript ID Adipose Adrenal Bladder Breast Colon Heart Kidney Liver Lung Ovary Placenta
ENSMUST00000026571 18.701±9.13 21.056±0.00 8.237±1.37 21.400±7.11 41.896±11.44 4.551±0.91 13.490±4.24 13.972±7.82 7.993±0.71 15.711±4.19 11.553±0.18
ENSMUST00000097952 N/A N/A N/A 5.996±0.00 N/A N/A N/A 7.480±3.30 N/A N/A N/A
ENSMUST00000106023 N/A N/A N/A N/A 19.281±5.45 N/A N/A 5.645±2.54 N/A N/A N/A
ENSMUST00000131399 N/A N/A N/A 17.312±0.00 N/A N/A N/A N/A N/A N/A N/A
ENSMUST00000155744 10.204±1.21 19.076±5.25 5.060±0.00 15.091±5.04 29.183±5.46 4.412±1.66 8.485±0.85 11.404±6.41 8.231±1.79 10.844±2.14 32.914±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006S8 CIL_0006S8_0003 CGP 7:141215860-141262750
CIL_0006RQ CIL_0006RQ_0003 CGP 7:141228784-141266481
CIL_0003OO CIL_0003OO_0002 CGP 7:141262706-141276786

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000975 IEA regulatory region DNA binding
GO:0000979 IEA RNA polymerase II core promoter sequence-specific DNA binding
GO:0000982 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity
GO:0002819 ISS regulation of adaptive immune response
GO:0003677 ISS DNA binding
GO:0005515 IPI protein binding
GO:0005634 IEA nucleus
GO:0005737 IEA cytoplasm
GO:0006357 IDA regulation of transcription from RNA polymerase II promoter
GO:0006366 IDA transcription from RNA polymerase II promoter
GO:0016064 IMP immunoglobulin mediated immune response
GO:0032607 IMP interferon-alpha production
GO:0032608 IMP interferon-beta production
GO:0032727 TAS positive regulation of interferon-alpha production
GO:0032728 TAS positive regulation of interferon-beta production
GO:0034124 IMP regulation of MyD88-dependent toll-like receptor signaling pathway
GO:0034127 IMP regulation of MyD88-independent toll-like receptor signaling pathway
GO:0045087 IEA innate immune response
GO:0045088 TAS regulation of innate immune response
GO:0045351 IMP type I interferon biosynthetic process
GO:0045893 ISS positive regulation of transcription, DNA-templated
GO:0045944 ISS positive regulation of transcription from RNA polymerase II promoter
GO:0060340 IMP positive regulation of type I interferon-mediated signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000045661 irf7 interferon regulatory factor 7 protein_coding Danio_rerio
ENSG00000185507 IRF7 interferon regulatory factor 7 protein_coding Homo_sapiens

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