C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), alpha su
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000025745 Hadha 10090 - 5:30118301-30155162 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000026843 Hadha-004 30119424-30154976 processed_transcript
  ENSMUST00000126081 Hadha-003 30121469-30127119 retained_intron
  ENSMUST00000130358 Hadha-002 30133235-30154962 retained_intron
  ENSMUST00000132486 Hadha-005 30119899-30120305 processed_transcript
  ENSMUST00000156859 Hadha-001 30118301-30155162 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000026843ENSMUST00000156859
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000026843 27.208±4.91 51.122±8.41 28.934±4.53 17.013±12.92 28.679±9.82 22.289±5.62 134.428±8.10 30.561±12.63 46.018±18.39 15.526±1.56 73.227±4.63 47.188±49.38 46.402±20.76 43.335±41.81
ENSMUST00000156859 15.291±12.60 19.823±2.67 N/A 6.235±1.47 31.239±8.76 17.086±9.17 19.662±0.82 41.350±1.38 22.869±10.92 4.244±0.09 20.002±5.11 11.653±8.88 6.102±1.53 14.622±5.71

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007DH CIL_0007DH_0002 CGP 5:30105161-30155162
CIL_0007DK CIL_0007DK_0002 CGP 5:30118301-30184593

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000062 IEA fatty-acyl-CoA binding
GO:0003988 IEA acetyl-CoA C-acyltransferase activity
GO:0004300 TAS enoyl-CoA hydratase activity
GO:0005515 IEA protein binding
GO:0005739 TAS mitochondrion
GO:0005743 IDA mitochondrial inner membrane
GO:0006635 IEA fatty acid beta-oxidation
GO:0016508 IEA long-chain-enoyl-CoA hydratase activity
GO:0016509 IDA long-chain-3-hydroxyacyl-CoA dehydrogenase activity
GO:0032403 IEA protein complex binding
GO:0032868 IMP response to insulin
GO:0042493 IEA response to drug
GO:0042645 IEA mitochondrial nucleoid
GO:0051287 IEA NAD binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000057128 hadhaa hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase, alpha subunit a protein_coding Danio_rerio
ENSDARG00000060594 hadhab hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase, alpha subunit b protein_coding Danio_rerio
ENSG00000084754 HADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit protein_coding Homo_sapiens

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