C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: serine/threonine kinase 17b (apoptosis-inducing)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000026094 Stk17b 10090 - 1:53755506-53785224 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000027263 Stk17b-001 53755506-53785224 protein_coding
  ENSMUST00000185920 Stk17b-003 53761149-53785157 protein_coding
  ENSMUST00000187066 Stk17b-002 53760573-53762693 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000027263ENSMUST00000187066
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000027263 4.401±0.69 2.661±0.80 7.412±3.30 0.721±0.12 13.919±8.20 18.649±6.42 1.862±0.45 2.467±0.71 3.343±2.36 10.676±0.76 1.611±0.49 6.515±3.61 5.456±1.88 4.913±1.58
ENSMUST00000187066 N/A 0.321±0.00 N/A N/A 3.083±0.00 N/A N/A N/A N/A N/A N/A 0.838±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002KA CIL_0002KA_0002 CGP 1:53397006-53785224
CIL_0002KD CIL_0002KD_0002 CGP 1:53755506-54195168

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004672 ISS protein kinase activity
GO:0004674 ISS protein serine/threonine kinase activity
GO:0005515 IEA protein binding
GO:0005524 ISS ATP binding
GO:0005634 ISS nucleus
GO:0005886 IEA plasma membrane
GO:0006468 ISS protein phosphorylation
GO:0006915 IEA apoptotic process
GO:0012501 IEA programmed cell death
GO:0015629 IEA actin cytoskeleton
GO:0035556 ISS intracellular signal transduction
GO:0046777 ISS protein autophosphorylation
GO:2000271 ISS positive regulation of fibroblast apoptotic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000014348 stk17b serine/threonine kinase 17b (apoptosis-inducing) protein_coding Danio_rerio
ENSG00000081320 STK17B serine/threonine kinase 17b protein_coding Homo_sapiens

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