C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: X-ray repair complementing defective repair in Chinese hamster cells 5
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000026187 Xrcc5 10090 + 1:72307421-72394952 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000027379 Xrcc5-201 72307421-72394952 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000027379
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000027379 2.493±1.38 0.712±0.33 8.748±0.53 4.420±0.84 1.425±0.52 1.604±0.33 2.140±0.17 7.513±0.29 5.227±2.92 2.734±0.32 7.829±1.43 4.481±4.33 8.621±4.93 2.744±0.77

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005ME CIL_0005ME_0002 CGP 1:72284369-72394952
CIL_0000AO CIL_0000AO_0003 CGP 1:72307421-72536930

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000723 IEA telomere maintenance
GO:0000784 IEA nuclear chromosome, telomeric region
GO:0003684 IEA damaged DNA binding
GO:0003690 IEA double-stranded DNA binding
GO:0003691 IEA double-stranded telomeric DNA binding
GO:0004003 IEA ATP-dependent DNA helicase activity
GO:0005515 IEA protein binding
GO:0005524 IEA ATP binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0006302 IGI double-strand break repair
GO:0006303 ISS double-strand break repair via nonhomologous end joining
GO:0006310 IEA DNA recombination
GO:0006351 IEA transcription, DNA-templated
GO:0007420 IEA brain development
GO:0008022 IEA protein C-terminus binding
GO:0008283 IMP cell proliferation
GO:0016020 IEA membrane
GO:0031625 IEA ubiquitin protein ligase binding
GO:0032508 IEA DNA duplex unwinding
GO:0042493 IEA response to drug
GO:0043234 IEA protein complex
GO:0043564 ISS Ku70:Ku80 complex
GO:0044212 IEA transcription regulatory region DNA binding
GO:0044822 IEA poly(A) RNA binding
GO:0045892 ISS negative regulation of transcription, DNA-templated
GO:0050769 IMP positive regulation of neurogenesis
GO:0051575 ISS 5'-deoxyribose-5-phosphate lyase activity
GO:0060218 IMP hematopoietic stem cell differentiation
GO:0070419 ISS nonhomologous end joining complex
GO:0071398 IEA cellular response to fatty acid
GO:0071475 IEA cellular hyperosmotic salinity response
GO:0071481 IEA cellular response to X-ray

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000015599 xrcc5 X-ray repair complementing defective repair in Chinese hamster cells 5 protein_coding Danio_rerio
ENSDARG00000068862 xrcc5 X-ray repair complementing defective repair in Chinese hamster cells 5 protein_coding Danio_rerio
ENSG00000079246 XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) protein_coding Homo_sapiens

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