C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000026192 Atic 10090 + 1:71557150-71579631 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000027384 Atic-001 71557150-71579631 protein_coding
  ENSMUST00000136443 Atic-003 71557213-71563198 retained_intron
  ENSMUST00000148077 Atic-002 71557179-71563198 retained_intron
  ENSMUST00000154855 Atic-005 71568866-71572960 retained_intron
  ENSMUST00000155769 Atic-004 71557179-71573363 retained_intron
  ENSMUST00000187982 Atic-006 71557179-71559951 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000027384ENSMUST00000155769
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000027384 15.931±3.25 5.752±0.91 17.709±2.02 10.660±2.03 8.802±1.33 9.311±0.94 6.421±0.31 7.842±1.34 15.156±10.87 6.778±1.02 7.478±1.46 14.207±4.11 21.897±12.47 3.018±0.41
ENSMUST00000155769 9.845±3.93 21.096±2.91 N/A N/A 11.150±3.27 10.385±1.61 2.301±0.32 3.133±0.68 3.432±2.09 4.353±0.91 N/A 23.582±2.69 N/A 1.293±0.40

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005MH CIL_0005MH_0002 CGP 1:71242276-71579631
CIL_0005MI CIL_0005MI_0002 CGP 1:71557150-71653200

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003360 IEA brainstem development
GO:0003937 IEA IMP cyclohydrolase activity
GO:0004643 IEA phosphoribosylaminoimidazolecarboxamide formyltransferase activity
GO:0005739 IDA mitochondrion
GO:0006189 IEA 'de novo' IMP biosynthetic process
GO:0009116 IEA nucleoside metabolic process
GO:0009259 IEA ribonucleotide metabolic process
GO:0010035 IEA response to inorganic substance
GO:0016020 IEA membrane
GO:0021549 IEA cerebellum development
GO:0021987 IEA cerebral cortex development
GO:0031100 IEA organ regeneration
GO:0042803 ISS protein homodimerization activity
GO:0046452 IEA dihydrofolate metabolic process
GO:0046654 IEA tetrahydrofolate biosynthetic process
GO:0070062 IEA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000016706 atic 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase protein_coding Danio_rerio
ENSG00000138363 ATIC 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase protein_coding Homo_sapiens

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