C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: regulator of G-protein signaling 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000026360 Rgs2 10090 - 1:143999338-144004161 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000027606 Rgs2-004 144001680-144004135 nonsense_mediated_decay
  ENSMUST00000127206 Rgs2-001 143999338-144004161 protein_coding
  ENSMUST00000134817 Rgs2-002 144002517-144004121 retained_intron
  ENSMUST00000153527 Rgs2-003 144001883-144004032 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000027606ENSMUST00000127206ENSMUST00000153527
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000027606 4.156±2.83 N/A 71.083±0.00 N/A N/A 2.461±0.47 2.889±0.00 1.829±0.39 N/A N/A 0.847±0.18 48.880±0.00 1.636±0.00 1.107±0.45
ENSMUST00000127206 3.136±2.32 5.470±0.78 18.879±4.65 13.025±3.42 3.418±0.55 2.537±0.55 4.083±1.81 2.261±0.34 0.975±0.66 9.331±3.41 0.833±0.36 18.173±10.91 1.511±1.04 1.077±0.43
ENSMUST00000153527 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.484±0.00 N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005096 IBA GTPase activator activity
GO:0005515 IPI protein binding
GO:0005634 TAS nucleus
GO:0005737 IBA cytoplasm
GO:0005829 IMP cytosol
GO:0005886 IBA plasma membrane
GO:0006417 IEA regulation of translation
GO:0007049 IEA cell cycle
GO:0007186 TAS G-protein coupled receptor signaling pathway
GO:0007283 IEP spermatogenesis
GO:0009898 IDA cytoplasmic side of plasma membrane
GO:0010519 IMP negative regulation of phospholipase activity
GO:0010614 IMP negative regulation of cardiac muscle hypertrophy
GO:0031116 IEA positive regulation of microtubule polymerization
GO:0038032 IEA termination of G-protein coupled receptor signaling pathway
GO:0043005 IEA neuron projection
GO:0043407 IMP negative regulation of MAP kinase activity
GO:0043547 IEA positive regulation of GTPase activity
GO:0043951 IMP negative regulation of cAMP-mediated signaling
GO:0045744 IMP negative regulation of G-protein coupled receptor protein signaling pathway
GO:0048487 IEA beta-tubulin binding
GO:0050873 IDA brown fat cell differentiation
GO:0055119 IMP relaxation of cardiac muscle
GO:0060087 IMP relaxation of vascular smooth muscle
GO:0060452 IMP positive regulation of cardiac muscle contraction
GO:0071877 IMP regulation of adrenergic receptor signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000056875 rgs2 regulator of G-protein signaling 2 protein_coding Danio_rerio
ENSG00000116741 RGS2 regulator of G-protein signaling 2 protein_coding Homo_sapiens

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