C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: ect2 oncogene
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000027699 Ect2 10090 - 3:27097222-27153878 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000108296 Ect2-004 27121878-27153812 retained_intron
  ENSMUST00000108298 Ect2-001 27097222-27153878 protein_coding
  ENSMUST00000108300 Ect2-002 27097222-27153861 protein_coding
  ENSMUST00000124727 Ect2-005 27131463-27137136 retained_intron
  ENSMUST00000150061 Ect2-006 27098306-27117807 nonsense_mediated_decay
  ENSMUST00000175857 Ect2-010 27146028-27153782 protein_coding
  ENSMUST00000176242 Ect2-201 27097223-27153854 protein_coding
  ENSMUST00000176535 Ect2-008 27145968-27153828 protein_coding
  ENSMUST00000176780 Ect2-007 27145020-27153854 protein_coding
  ENSMUST00000176908 Ect2-011 27117852-27122692 retained_intron
  ENSMUST00000177055 Ect2-009 27145984-27153810 protein_coding
  ENSMUST00000184113 Ect2-003 27097226-27153850 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000108296ENSMUST00000108298ENSMUST00000108300ENSMUST00000150061ENSMUST00000176242ENSMUST00000176535ENSMUST00000176780ENSMUST00000176908ENSMUST00000184113
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000108296 N/A 0.651±0.18 N/A 0.057±0.00 0.302±0.19 N/A N/A N/A N/A 0.114±0.00 N/A 1.317±0.95 2.697±2.37 1.613±0.00
ENSMUST00000108298 1.528±0.90 N/A 0.143±0.03 4.104±1.44 0.248±0.00 1.879±0.48 N/A 1.172±0.65 7.900±5.08 N/A N/A 1.142±0.44 4.217±3.59 2.948±0.25
ENSMUST00000108300 N/A 0.600±0.19 N/A 0.575±0.00 0.408±0.12 0.812±0.49 N/A N/A 0.413±0.68 0.231±0.03 0.042±0.00 2.359±0.93 3.083±1.60 1.193±0.00
ENSMUST00000150061 0.710±0.00 N/A N/A 0.162±0.00 N/A N/A N/A N/A 0.213±0.09 N/A 0.039±0.00 1.859±1.23 4.681±3.39 N/A
ENSMUST00000176242 N/A 0.121±0.04 0.220±0.04 1.772±0.76 0.037±0.00 N/A 0.086±0.03 0.963±0.20 2.315±2.19 0.200±0.09 N/A 1.708±0.17 3.192±0.72 1.881±0.49
ENSMUST00000176535 N/A N/A N/A 0.167±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENSMUST00000176780 N/A N/A N/A 0.098±0.00 N/A N/A N/A N/A N/A N/A 0.085±0.00 N/A N/A 8.031±0.00
ENSMUST00000176908 N/A N/A N/A N/A 0.196±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENSMUST00000184113 0.200±0.00 N/A N/A N/A 0.058±0.00 0.303±0.00 0.070±0.03 0.311±0.14 N/A N/A 0.040±0.03 1.190±0.00 N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000902 IDA cell morphogenesis
GO:0000910 IEA:ISS cytokinesis
GO:0004871 IEA signal transducer activity
GO:0005085 IEA guanyl-nucleotide exchange factor activity
GO:0005089 ISS Rho guanyl-nucleotide exchange factor activity
GO:0005096 IEA:ISS GTPase activator activity
GO:0005515 IPI protein binding
GO:0005634 IEA:IDA nucleus
GO:0005737 IEA:IDA cytoplasm
GO:0005911 ISS cell-cell junction
GO:0005923 ISS tight junction
GO:0015031 IEA protein transport
GO:0017048 IPI Rho GTPase binding
GO:0030496 ISS midbody
GO:0032147 ISS activation of protein kinase activity
GO:0032154 ISS cleavage furrow
GO:0032321 ISS positive regulation of Rho GTPase activity
GO:0032467 ISS positive regulation of cytokinesis
GO:0032862 ISS activation of Rho GTPase activity
GO:0032863 ISS activation of Rac GTPase activity
GO:0035556 IEA intracellular signal transduction
GO:0042307 IDA positive regulation of protein import into nucleus
GO:0042803 ISS protein homodimerization activity
GO:0043065 ISS positive regulation of apoptotic process
GO:0043089 ISS positive regulation of Cdc42 GTPase activity
GO:0043123 IEA positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043547 IEA positive regulation of GTPase activity
GO:0045666 IEA:IMP positive regulation of neuron differentiation
GO:0045859 ISS regulation of protein kinase activity
GO:0051260 ISS protein homooligomerization
GO:0051988 ISS regulation of attachment of spindle microtubules to kinetochore
GO:0070301 ISS cellular response to hydrogen peroxide
GO:0070830 ISS tight junction assembly
GO:0071277 ISS cellular response to calcium ion
GO:0071479 ISS cellular response to ionizing radiation
GO:0072686 ISS mitotic spindle
GO:0097149 ISS centralspindlin complex

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000007278 ect2 epithelial cell transforming sequence 2 oncogene protein_coding Danio_rerio
ENSG00000114346 ECT2 epithelial cell transforming 2 protein_coding Homo_sapiens

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