C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: protease, serine 12 neurotrypsin (motopsin)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000027978 Prss12 10090 + 3:123446913-123506602 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000029603 Prss12-201 123446913-123506602 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000029603
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000029603 1.183±0.59 1.515±0.36 0.375±0.04 10.921±12.31 2.913±1.25 0.393±0.13 0.312±0.07 0.748±0.16 0.179±0.17 3.563±0.81 0.253±0.10 0.911±0.49 5.403±3.82 0.173±0.08

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00005Q CIL_00005Q_0002 CGP 3:123364645-123506602
CIL_0003I1 CIL_0003I1_0002 CGP 3:123446913-123690852

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004252 IDA serine-type endopeptidase activity
GO:0005044 IEA scavenger receptor activity
GO:0005576 IEA extracellular region
GO:0005886 IDA plasma membrane
GO:0006508 IDA proteolysis
GO:0006887 IDA exocytosis
GO:0006898 IEA receptor-mediated endocytosis
GO:0008233 IMP peptidase activity
GO:0030424 IDA axon
GO:0030425 IDA dendrite
GO:0031410 IDA cytoplasmic vesicle
GO:0031638 IDA zymogen activation
GO:0043083 IDA synaptic cleft
GO:0043195 IDA terminal bouton
GO:0045202 IDA synapse

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000061830 prss12 protease, serine, 12 (neurotrypsin, motopsin) protein_coding Danio_rerio
ENSG00000164099 PRSS12 protease, serine, 12 (neurotrypsin, motopsin) protein_coding Homo_sapiens

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