C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: late endosomal/lysosomal adaptor, MAPK and MTOR activator 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000028062 Lamtor2 10090 - 3:88549819-88553074 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000029698 Lamtor2-001 88549819-88553024 protein_coding
  ENSMUST00000119002 Lamtor2-003 88549820-88552859 protein_coding
  ENSMUST00000145172 Lamtor2-002 88552230-88553074 retained_intron
  ENSMUST00000145548 Lamtor2-005 88549819-88551094 retained_intron
  ENSMUST00000156421 Lamtor2-004 88549821-88552893 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000029698ENSMUST00000119002ENSMUST00000145172ENSMUST00000145548
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000029698 55.879±9.41 34.806±9.36 62.636±1.96 57.208±22.78 35.805±11.00 56.138±11.30 37.670±7.67 99.096±16.29 91.102±17.21 53.325±3.66 40.278±4.20 46.438±29.86 113.220±86.12 20.906±3.24
ENSMUST00000119002 N/A N/A N/A 38.097±0.00 20.852±0.00 N/A N/A N/A N/A N/A 9.645±1.57 41.664±1.17 24.770±4.10 N/A
ENSMUST00000145172 28.751±5.20 45.971±9.64 N/A 27.139±18.06 37.358±5.42 66.488±7.78 16.430±1.59 39.200±12.05 15.122±0.00 20.034±2.79 N/A 41.982±9.83 N/A 11.458±4.20
ENSMUST00000145548 N/A N/A N/A N/A 4.665±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008P5 CIL_0008P5_0002 VISTA 3:88218217-88823366
CIL_000898 CIL_000898_0002 VISTA 3:88224783-88827970
CIL_00064T CIL_00064T_0002 CGP 3:88549819-88569725

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000186 IDA activation of MAPKK activity
GO:0005085 ISS guanyl-nucleotide exchange factor activity
GO:0005515 IPI protein binding
GO:0005765 IEA lysosomal membrane
GO:0005770 IDA late endosome
GO:0016049 ISS cell growth
GO:0032008 ISS positive regulation of TOR signaling
GO:0032947 ISS protein complex scaffold
GO:0034613 ISS cellular protein localization
GO:0043547 ISS positive regulation of GTPase activity
GO:0070062 IEA extracellular vesicular exosome
GO:0071230 ISS cellular response to amino acid stimulus
GO:0071986 ISS Ragulator complex

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000039872 lamtor2 late endosomal/lysosomal adaptor, MAPK and MTOR activator 2 protein_coding Danio_rerio
ENSG00000116586 LAMTOR2 late endosomal/lysosomal adaptor, MAPK and MTOR activator 2 protein_coding Homo_sapiens

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