C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: phosphatidylinositol-4-phosphate 5-kinase, type 1 alpha
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000028126 Pip5k1a 10090 - 3:95058530-95106930 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000005768 Pip5k1a-004 95058569-95106779 protein_coding
  ENSMUST00000107229 Pip5k1a-005 95097043-95106823 processed_transcript
  ENSMUST00000107231 Pip5k1a-007 95070826-95078516 processed_transcript
  ENSMUST00000107232 Pip5k1a-009 95058545-95106856 protein_coding
  ENSMUST00000107233 Pip5k1a-001 95058543-95106930 protein_coding
  ENSMUST00000107236 Pip5k1a-002 95058530-95106875 protein_coding
  ENSMUST00000151335 Pip5k1a-008 95078105-95083232 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000005768ENSMUST00000107232ENSMUST00000107233ENSMUST00000107236
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000005768 1.675±0.45 N/A 3.320±0.18 4.542±2.08 1.922±0.77 2.263±0.00 0.982±0.38 3.487±2.00 1.496±1.07 N/A 3.294±1.68 5.455±2.00 10.195±6.88 1.660±0.00
ENSMUST00000107232 N/A 2.562±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENSMUST00000107233 1.055±0.00 N/A 3.902±0.45 3.764±0.63 1.418±0.00 1.592±0.12 0.731±0.00 1.218±0.03 1.863±1.16 2.592±0.00 1.259±0.13 2.063±0.00 7.817±2.78 1.340±0.59
ENSMUST00000107236 2.049±0.71 2.513±0.28 4.850±0.37 3.035±1.69 1.854±0.00 N/A 1.110±0.23 1.350±0.28 3.021±1.53 2.139±0.33 1.462±0.11 3.284±1.21 10.085±4.24 1.747±0.11

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005634 IDA nucleus
GO:0005737 IEA cytoplasm
GO:0005847 IEA mRNA cleavage and polyadenylation specificity factor complex
GO:0005886 ISS plasma membrane
GO:0005925 IEA focal adhesion
GO:0008654 IEA phospholipid biosynthetic process
GO:0010761 IMP fibroblast migration
GO:0016308 IDA 1-phosphatidylinositol-4-phosphate 5-kinase activity
GO:0016607 ISS nuclear speck
GO:0019900 IEA kinase binding
GO:0030027 IEA lamellipodium
GO:0031532 ISS actin cytoskeleton reorganization
GO:0032587 IDA ruffle membrane
GO:0032863 ISS activation of Rac GTPase activity
GO:0046488 IDA phosphatidylinositol metabolic process
GO:0046854 IEA phosphatidylinositol phosphorylation
GO:0048041 ISS focal adhesion assembly
GO:0060326 ISS cell chemotaxis
GO:0072661 ISS protein targeting to plasma membrane
GO:0097178 ISS ruffle assembly

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000002614 pip5k1aa phosphatidylinositol-4-phosphate 5-kinase, type I, alpha, a protein_coding Danio_rerio
ENSDARG00000024642 pip5k1ab phosphatidylinositol-4-phosphate 5-kinase, type I, alpha, b protein_coding Danio_rerio
ENSG00000143398 PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha protein_coding Homo_sapiens

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