C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: SH3-domain GRB2-like 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000028488 Sh3gl2 10090 + 4:85205126-85639195 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000030212 Sh3gl2-001 85205441-85389380 protein_coding
  ENSMUST00000107184 Sh3gl2-004 85205535-85377691 protein_coding
  ENSMUST00000107188 Sh3gl2-002 85205126-85399529 protein_coding
  ENSMUST00000107189 Sh3gl2-003 85205469-85639195 protein_coding
  ENSMUST00000133109 Sh3gl2-005 85376341-85387604 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000030212ENSMUST00000107184ENSMUST00000107188ENSMUST00000107189ENSMUST00000133109
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000030212 1.910±1.85 5.710±2.01 61.432±4.75 17.280±4.16 0.256±0.16 6.558±1.98 0.288±0.05 5.532±0.68 0.039±0.03 1.486±0.23 0.049±0.02 3.177±1.03 0.162±0.19 5.122±2.42
ENSMUST00000107184 N/A N/A N/A N/A N/A N/A N/A N/A 0.037±0.00 N/A N/A N/A 0.052±0.00 6.284±0.00
ENSMUST00000107188 N/A N/A N/A N/A N/A 1.207±0.00 N/A N/A N/A N/A N/A 0.670±0.00 N/A N/A
ENSMUST00000107189 0.012±0.00 N/A N/A N/A N/A N/A N/A N/A 0.008±0.00 N/A N/A N/A N/A N/A
ENSMUST00000133109 N/A N/A N/A 141.820±0.00 N/A N/A N/A N/A 0.063±0.00 N/A 0.052±0.03 4.810±0.00 0.045±0.00 3.953±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008E9 CIL_0008E9_0002 VISTA 4:84686009-85288497
CIL_0007VQ CIL_0007VQ_0002 VISTA 4:84695828-85296432
CIL_00013X CIL_00013X_0002 CGP 4:84884309-85639195
CIL_00013Y CIL_00013Y_0002 CGP 4:85205126-86428385

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002090 IDA regulation of receptor internalization
GO:0005515 IPI protein binding
GO:0005737 IEA cytoplasm
GO:0008289 IEA lipid binding
GO:0016020 IEA membrane
GO:0042802 IEA identical protein binding
GO:0048488 IGI synaptic vesicle endocytosis
GO:0070062 IEA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000023600 sh3gl2 SH3-domain GRB2-like 2 protein_coding Danio_rerio
ENSDARG00000039901 SH3GL2 (2 of 2) SH3-domain GRB2-like 2 protein_coding Danio_rerio
ENSG00000107295 SH3GL2 SH3-domain GRB2-like 2 protein_coding Homo_sapiens

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