C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: angiopoietin-like 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000028553 Angptl3 10090 + 4:99030954-99046111 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000030280 Angptl3-001 99030954-99038065 protein_coding
  ENSMUST00000125546 Angptl3-002 99033203-99046111 processed_transcript
  ENSMUST00000136091 Angptl3-003 99033179-99037959 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000030280ENSMUST00000125546ENSMUST00000136091
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000030280 0.092±0.04 0.448±0.00 0.038±0.00 0.089±0.00 0.197±0.03 0.090±0.00 0.053±0.00 2.551±0.41 80.501±51.51 0.078±0.00 0.049±0.03 0.280±0.22 0.750±0.67 0.015±0.00
ENSMUST00000125546 0.063±0.03 0.064±0.03 0.085±0.00 0.199±0.14 0.091±0.07 0.037±0.00 0.047±0.01 N/A N/A 0.052±0.01 N/A 0.101±0.06 0.026±0.00 0.022±0.01
ENSMUST00000136091 0.324±0.11 0.410±0.20 N/A 0.599±0.00 0.400±0.00 N/A 0.384±0.18 3.564±0.35 77.224±9.29 0.327±0.15 N/A 0.459±0.17 0.232±0.05 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002G2 CIL_0002G2_0002 CGP 4:98923810-99120915
CIL_000051 CIL_000051_0003 CGP 4:98936665-99120915
CIL_0008H9 CIL_0008H9_0002 VISTA 4:98994411-99595982
CIL_0002G5 CIL_0002G5_0002 CGP 4:99030954-99259787

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004857 IDA enzyme inhibitor activity
GO:0004859 IEA phospholipase inhibitor activity
GO:0005178 ISS integrin binding
GO:0005576 ISS extracellular region
GO:0005615 IEA extracellular space
GO:0006071 IEA glycerol metabolic process
GO:0006631 IEA fatty acid metabolic process
GO:0006641 NAS triglyceride metabolic process
GO:0006644 IEA phospholipid metabolic process
GO:0007160 ISS cell-matrix adhesion
GO:0007165 IEA signal transduction
GO:0008083 IEA growth factor activity
GO:0008203 IEA cholesterol metabolic process
GO:0009395 IEA phospholipid catabolic process
GO:0009986 IEA cell surface
GO:0010519 IMP negative regulation of phospholipase activity
GO:0019915 IEA lipid storage
GO:0030335 ISS positive regulation of cell migration
GO:0042632 IMP cholesterol homeostasis
GO:0045766 ISS positive regulation of angiogenesis
GO:0045834 NAS positive regulation of lipid metabolic process
GO:0048844 IMP artery morphogenesis
GO:0050996 IEA positive regulation of lipid catabolic process
GO:0051005 IEA negative regulation of lipoprotein lipase activity
GO:0055088 IEA lipid homeostasis
GO:0055090 IMP acylglycerol homeostasis
GO:0055091 IMP phospholipid homeostasis
GO:0070328 IMP triglyceride homeostasis

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000044365 angptl3 angiopoietin-like 3 protein_coding Danio_rerio
ENSG00000132855 ANGPTL3 angiopoietin-like 3 protein_coding Homo_sapiens

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