C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: histone deacetylase 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000028800 Hdac1 10090 - 4:129516104-129542713 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000102597 Hdac1-001 129516104-129542713 protein_coding
  ENSMUST00000125718 Hdac1-003 129522491-129528999 retained_intron
  ENSMUST00000132909 Hdac1-006 129522826-129524542 retained_intron
  ENSMUST00000139305 Hdac1-002 129528515-129542691 retained_intron
  ENSMUST00000142984 Hdac1-005 129518083-129522790 retained_intron
  ENSMUST00000145628 Hdac1-007 129516268-129517518 retained_intron
  ENSMUST00000150105 Hdac1-004 129522638-129524584 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000102597ENSMUST00000125718ENSMUST00000142984
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000102597 25.527±5.29 3.790±0.83 37.999±3.93 23.306±15.39 19.387±3.94 28.132±2.67 7.291±0.61 16.455±1.24 31.066±26.04 21.678±3.92 4.080±0.69 15.513±7.42 51.354±21.05 51.128±15.19
ENSMUST00000125718 N/A 3.427±0.07 N/A 4.916±0.00 N/A N/A N/A N/A N/A N/A N/A 8.898±1.71 N/A N/A
ENSMUST00000142984 N/A 4.894±0.55 N/A N/A 10.873±1.43 11.291±1.95 N/A N/A 3.158±0.00 7.090±0.00 N/A 7.868±1.49 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008AA CIL_0008AA_0002 VISTA 4:129413466-130014337
CIL_0002A7 CIL_0002A7_0002 CGP 4:129513581-129542713

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000118 TAS histone deacetylase complex
GO:0000122 IGI negative regulation of transcription from RNA polymerase II promoter
GO:0000790 IDA nuclear chromatin
GO:0000792 IDA heterochromatin
GO:0000976 IDA transcription regulatory region sequence-specific DNA binding
GO:0001047 IDA core promoter binding
GO:0001103 IPI RNA polymerase II repressing transcription factor binding
GO:0003677 IDA DNA binding
GO:0003682 IDA chromatin binding
GO:0003700 IDA sequence-specific DNA binding transcription factor activity
GO:0003714 IDA transcription corepressor activity
GO:0004407 IDA histone deacetylase activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005667 IPI transcription factor complex
GO:0005737 TAS cytoplasm
GO:0006351 IEA transcription, DNA-templated
GO:0007492 IDA endoderm development
GO:0007623 IDA circadian rhythm
GO:0008134 TAS transcription factor binding
GO:0008284 IGI positive regulation of cell proliferation
GO:0009913 IGI epidermal cell differentiation
GO:0016568 TAS chromatin modification
GO:0016581 IDA NuRD complex
GO:0017053 IPI transcriptional repressor complex
GO:0019213 IDA deacetylase activity
GO:0021766 IGI hippocampus development
GO:0030182 IGI neuron differentiation
GO:0032041 IEA NAD-dependent histone deacetylase activity (H3-K14 specific)
GO:0032922 IDA circadian regulation of gene expression
GO:0035851 IPI Krueppel-associated box domain binding
GO:0042475 IGI odontogenesis of dentin-containing tooth
GO:0042733 IGI embryonic digit morphogenesis
GO:0043025 IDA neuronal cell body
GO:0043066 IGI negative regulation of apoptotic process
GO:0043124 IGI negative regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043234 IDA protein complex
GO:0045892 IDA negative regulation of transcription, DNA-templated
GO:0046969 IEA NAD-dependent histone deacetylase activity (H3-K9 specific)
GO:0046970 IEA NAD-dependent histone deacetylase activity (H4-K16 specific)
GO:0048714 IGI positive regulation of oligodendrocyte differentiation
GO:0060789 IGI hair follicle placode formation
GO:0061029 IGI eyelid development in camera-type eye
GO:0061198 IGI fungiform papilla formation
GO:0070932 IDA histone H3 deacetylation
GO:0070933 IDA histone H4 deacetylation
GO:0090090 IGI negative regulation of canonical Wnt signaling pathway
GO:0097372 IEA NAD-dependent histone deacetylase activity (H3-K18 specific)
GO:2001243 IGI negative regulation of intrinsic apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000015427 hdac1 histone deacetylase 1 protein_coding Danio_rerio
ENSG00000116478 HDAC1 histone deacetylase 1 protein_coding Homo_sapiens

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