C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: mitofusin 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000029020 Mfn2 10090 - 4:147873599-147904704 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000030884 Mfn2-002 147873599-147904704 protein_coding
  ENSMUST00000105714 Mfn2-003 147881494-147904698 protein_coding
  ENSMUST00000105715 Mfn2-004 147874016-147904698 protein_coding
  ENSMUST00000105716 Mfn2-001 147873599-147904687 protein_coding
  ENSMUST00000124646 Mfn2-008 147885708-147887523 processed_transcript
  ENSMUST00000134172 Mfn2-007 147887334-147903395 protein_coding
  ENSMUST00000150881 Mfn2-006 147894583-147904658 protein_coding

Mus musculus EnsemblGRCm38

Genome
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Genes
Gene structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000030884ENSMUST00000105715ENSMUST00000105716ENSMUST00000134172
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000030884 N/A N/A 4.411±0.55 N/A 24.743±1.33 N/A 183.964±4.22 N/A N/A 6.525±0.51 124.622±5.49 N/A N/A N/A
ENSMUST00000105715 N/A 7.560±1.01 N/A 8.059±0.00 N/A N/A N/A N/A N/A N/A N/A 3.649±0.00 8.252±0.00 17.331±3.42
ENSMUST00000105716 48.922±13.97 57.660±6.28 21.457±1.53 28.331±5.03 37.548±8.21 33.794±1.57 N/A 36.965±4.26 17.669±9.48 20.742±4.16 N/A 24.086±4.92 21.252±5.22 35.144±10.40
ENSMUST00000134172 N/A N/A N/A 115.652±0.00 N/A N/A N/A N/A N/A N/A N/A 47.022±0.00 72.200±14.52 85.150±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00087H CIL_00087H_0002 VISTA 4:147665245-148272946

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001825 IMP blastocyst formation
GO:0003924 IEA GTPase activity
GO:0005515 IPI protein binding
GO:0005525 IEA GTP binding
GO:0005739 IDA mitochondrion
GO:0005829 ISS cytosol
GO:0006184 IEA GTP catabolic process
GO:0006626 ISS protein targeting to mitochondrion
GO:0006914 IEA autophagy
GO:0006915 IEA apoptotic process
GO:0006986 IEA response to unfolded protein
GO:0007006 ISS mitochondrial membrane organization
GO:0008053 IMP mitochondrial fusion
GO:0015630 IDA microtubule cytoskeleton
GO:0016021 IEA integral component of membrane
GO:0031306 ISS intrinsic component of mitochondrial outer membrane
GO:0031625 IEA ubiquitin protein ligase binding
GO:0034497 IEA protein localization to pre-autophagosomal structure
GO:0046580 IEA negative regulation of Ras protein signal transduction
GO:0048593 IMP camera-type eye morphogenesis
GO:0048662 IEA:ISS negative regulation of smooth muscle cell proliferation
GO:0051646 ISS mitochondrion localization

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000079504 mfn2 mitofusin 2 protein_coding Danio_rerio
ENSG00000116688 MFN2 mitofusin 2 protein_coding Homo_sapiens

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