C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: steroid 5 alpha-reductase 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000029233 Srd5a3 10090 + 5:76140271-76155504 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000031143 Srd5a3-001 76140271-76155479 protein_coding
  ENSMUST00000113506 Srd5a3-005 76147961-76155246 protein_coding
  ENSMUST00000113507 Srd5a3-004 76146637-76155244 protein_coding
  ENSMUST00000124217 Srd5a3-007 76152769-76155504 retained_intron
  ENSMUST00000127278 Srd5a3-008 76140730-76149947 protein_coding
  ENSMUST00000138699 Srd5a3-006 76140271-76151515 retained_intron
  ENSMUST00000149222 Srd5a3-002 76140306-76140862 processed_transcript
  ENSMUST00000152642 Srd5a3-003 76140700-76149755 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000031143ENSMUST00000113506ENSMUST00000113507ENSMUST00000124217ENSMUST00000138699ENSMUST00000149222
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000031143 22.910±5.45 23.500±4.07 9.956±0.27 2.591±1.51 18.749±3.21 16.562±2.15 4.619±0.78 10.807±3.02 6.750±1.48 23.117±2.12 0.819±0.30 21.730±11.34 11.288±10.08 1.900±0.51
ENSMUST00000113506 N/A N/A N/A N/A 25.920±0.00 N/A N/A N/A 2.234±0.00 N/A 0.689±0.00 8.680±0.56 9.590±2.46 N/A
ENSMUST00000113507 9.151±1.92 N/A 3.939±0.00 1.251±0.29 6.609±0.00 N/A 3.887±0.87 6.876±1.85 3.245±0.90 N/A 0.898±0.28 3.122±0.86 6.594±0.00 1.164±0.83
ENSMUST00000124217 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.207±0.00 2.153±0.00 0.663±0.00 N/A
ENSMUST00000138699 N/A N/A N/A 0.233±0.00 N/A N/A N/A N/A N/A N/A 0.175±0.00 0.449±0.00 N/A 0.035±0.00
ENSMUST00000149222 69.618±4.93 232.779±70.73 N/A N/A 66.323±18.59 47.677±6.46 N/A 21.409±0.63 12.610±1.96 51.696±10.66 N/A 68.417±24.87 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00025J CIL_00025J_0002 CGP 5:75932827-76155504
CIL_00025I CIL_00025I_0002 CGP 5:76140271-76209245

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003865 ISS 3-oxo-5-alpha-steroid 4-dehydrogenase activity
GO:0005783 ISS endoplasmic reticulum
GO:0006486 IEA protein glycosylation
GO:0006488 IMP dolichol-linked oligosaccharide biosynthetic process
GO:0016021 IEA integral component of membrane
GO:0016095 IMP polyprenol catabolic process
GO:0016628 ISS oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor
GO:0019348 IMP dolichol metabolic process
GO:0047751 IEA cholestenone 5-alpha-reductase activity
GO:0055114 IEA oxidation-reduction process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000043307 srd5a3 steroid 5 alpha-reductase 3 protein_coding Danio_rerio
ENSG00000128039 SRD5A3 steroid 5 alpha-reductase 3 protein_coding Homo_sapiens

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