C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: circadian locomotor output cycles kaput
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000029238 Clock 10090 - 5:76212177-76304548 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000075159 Clock-201 76212177-76304548 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000075159
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000075159 9.935±3.36 13.128±1.70 2.706±0.03 2.408±0.24 9.844±1.32 12.478±2.87 6.011±0.28 6.906±1.43 4.820±3.96 9.382±2.10 1.305±0.33 9.770±5.45 2.947±1.46 3.441±1.03

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00025L CIL_00025L_0002 CGP 5:76183880-76304548
CIL_00025K CIL_00025K_0002 CGP 5:76212177-76331156

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000077 IEA DNA damage checkpoint
GO:0000978 IEA RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0000982 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity
GO:0001046 IDA core promoter sequence-specific DNA binding
GO:0001047 IDA core promoter binding
GO:0001077 IC RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0001190 IDA RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription
GO:0003677 ISS DNA binding
GO:0003700 ISA sequence-specific DNA binding transcription factor activity
GO:0004402 IMP histone acetyltransferase activity
GO:0004871 IEA signal transducer activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0005667 IDA transcription factor complex
GO:0005694 IEA chromosome
GO:0005737 IDA cytoplasm
GO:0005829 TAS cytosol
GO:0006355 IDA regulation of transcription, DNA-templated
GO:0006366 IDA transcription from RNA polymerase II promoter
GO:0007165 IEA signal transduction
GO:0007283 IMP spermatogenesis
GO:0007623 IMP circadian rhythm
GO:0008134 ISA transcription factor binding
GO:0016573 IEA histone acetylation
GO:0031490 IDA chromatin DNA binding
GO:0032922 IMP circadian regulation of gene expression
GO:0033391 IDA chromatoid body
GO:0042634 ISS regulation of hair cycle
GO:0043161 IDA proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0043231 IEA intracellular membrane-bounded organelle
GO:0043565 IDA sequence-specific DNA binding
GO:0045892 IDA negative regulation of transcription, DNA-templated
GO:0045893 IDA positive regulation of transcription, DNA-templated
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0046983 IEA protein dimerization activity
GO:0050729 IMP positive regulation of inflammatory response
GO:0050796 IMP regulation of insulin secretion
GO:0051092 IMP positive regulation of NF-kappaB transcription factor activity
GO:0051775 ISS response to redox state
GO:0070888 IDA E-box binding
GO:0071479 IEA cellular response to ionizing radiation
GO:2000074 IMP regulation of type B pancreatic cell development
GO:2000323 IDA negative regulation of glucocorticoid receptor signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000003631 clock3 clock homolog 3 (mouse) protein_coding Danio_rerio
ENSDARG00000011703 clock clock protein_coding Danio_rerio
ENSG00000134852 CLOCK clock circadian regulator protein_coding Homo_sapiens

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