C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: protein kinase, cGMP-dependent, type II
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000029334 Prkg2 10090 - 5:98929773-99037351 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000031277 Prkg2-002 98931720-99037035 protein_coding
  ENSMUST00000160765 Prkg2-004 98947393-98966756 retained_intron
  ENSMUST00000161490 Prkg2-001 98929773-99037351 protein_coding
  ENSMUST00000162147 Prkg2-003 98931268-98943834 retained_intron
  ENSMUST00000162619 Prkg2-005 98931268-98943832 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000031277ENSMUST00000160765ENSMUST00000161490ENSMUST00000162147ENSMUST00000162619
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000031277 N/A 0.295±0.10 N/A 2.334±0.00 0.120±0.06 N/A 0.010±0.00 0.151±0.05 0.019±0.01 0.934±0.28 0.089±0.03 0.178±0.04 0.175±0.07 0.013±0.00
ENSMUST00000160765 0.110±0.00 N/A N/A N/A 0.359±0.00 N/A N/A N/A N/A N/A N/A N/A 1.940±0.00 N/A
ENSMUST00000161490 0.188±0.15 0.682±0.04 0.171±0.01 0.570±0.51 0.111±0.06 1.956±0.77 0.039±0.01 0.091±0.02 0.011±0.01 2.397±0.59 0.103±0.05 0.298±0.20 0.431±0.36 0.009±0.00
ENSMUST00000162147 N/A N/A N/A N/A N/A N/A N/A N/A 0.004±0.00 N/A N/A N/A 0.092±0.00 N/A
ENSMUST00000162619 N/A N/A N/A N/A 0.133±0.00 N/A N/A N/A 0.085±0.00 N/A N/A N/A 0.031±0.00 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00052T CIL_00052T_0003 CGP 5:98854439-99037351
CIL_000086 CIL_000086_0003 CGP 5:98929773-99252927

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004692 IEA cGMP-dependent protein kinase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005886 IDA plasma membrane
GO:0006468 IEA protein phosphorylation
GO:0007623 IMP circadian rhythm
GO:0016020 IEA membrane
GO:0030553 IEA cGMP binding
GO:0031965 IEA nuclear membrane
GO:0032922 IMP circadian regulation of gene expression
GO:0036289 IEA peptidyl-serine autophosphorylation
GO:0042803 IEA protein homodimerization activity
GO:0072661 IEA protein targeting to plasma membrane

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000054741 prkg2 protein kinase, cGMP-dependent, type II protein_coding Danio_rerio
ENSG00000138669 PRKG2 protein kinase, cGMP-dependent, type II protein_coding Homo_sapiens

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