C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: PAN3 polyA specific ribonuclease subunit homolog (S. cerevisiae)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000029647 Pan3 10090 + 5:147430161-147548502 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000031651 Pan3-001 147430161-147548502 protein_coding
  ENSMUST00000175807 Pan3-006 147519687-147548496 protein_coding
  ENSMUST00000176202 Pan3-008 147430896-147455336 retained_intron
  ENSMUST00000176357 Pan3-011 147453258-147492524 processed_transcript
  ENSMUST00000176466 Pan3-009 147430896-147527026 nonsense_mediated_decay
  ENSMUST00000176505 Pan3-007 147529733-147548488 retained_intron
  ENSMUST00000176553 Pan3-017 147539277-147548493 protein_coding
  ENSMUST00000176596 Pan3-005 147453289-147548496 nonsense_mediated_decay
  ENSMUST00000176600 Pan3-002 147430453-147548496 protein_coding
  ENSMUST00000176753 Pan3-003 147450660-147545945 protein_coding
  ENSMUST00000176806 Pan3-013 147529938-147531745 retained_intron
  ENSMUST00000176817 Pan3-014 147530014-147533353 processed_transcript
  ENSMUST00000176856 Pan3-015 147537216-147545680 processed_transcript
  ENSMUST00000177327 Pan3-010 147450656-147488453 retained_intron
  ENSMUST00000177328 Pan3-012 147519434-147527007 retained_intron
  ENSMUST00000177465 Pan3-004 147450660-147545945 nonsense_mediated_decay
  ENSMUST00000177496 Pan3-016 147536324-147543125 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000031651ENSMUST00000175807ENSMUST00000176505ENSMUST00000176553ENSMUST00000176596ENSMUST00000176600ENSMUST00000176753ENSMUST00000176817
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000031651 3.051±0.92 N/A 4.436±0.25 3.721±0.09 2.937±0.81 2.352±0.30 0.872±0.16 4.371±0.41 2.780±0.91 3.856±0.74 0.518±0.00 1.530±0.00 3.444±1.29 4.684±0.86
ENSMUST00000175807 N/A N/A N/A 0.734±0.00 N/A N/A N/A N/A 1.243±0.00 N/A 0.792±0.00 N/A 3.196±1.52 2.993±0.00
ENSMUST00000176505 N/A N/A N/A N/A N/A N/A N/A N/A 2.277±0.00 N/A N/A N/A N/A N/A
ENSMUST00000176553 N/A N/A N/A N/A 17.182±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENSMUST00000176596 1.728±0.00 N/A N/A 1.554±0.63 4.296±2.05 2.450±0.00 1.501±0.61 2.210±0.20 1.775±0.87 2.687±0.00 0.380±0.01 3.925±1.00 2.136±0.53 9.330±3.06
ENSMUST00000176600 2.407±0.74 4.744±0.31 N/A 2.012±0.86 6.192±0.73 5.715±0.81 N/A N/A 1.917±1.22 3.572±0.00 0.265±0.00 6.828±1.75 1.520±0.28 5.041±0.51
ENSMUST00000176753 1.992±0.00 N/A N/A N/A 4.989±1.78 N/A 1.336±0.12 N/A 1.495±0.55 6.531±0.00 N/A 7.684±0.62 9.571±0.00 6.512±0.11
ENSMUST00000176817 N/A N/A N/A 32.430±0.00 N/A N/A N/A N/A N/A N/A N/A N/A 63.359±3.40 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008CO CIL_0008CO_0002 VISTA 5:146855041-147456530
CIL_00082E CIL_00082E_0002 VISTA 5:146922660-147524221
CIL_0007MT CIL_0007MT_0002 UCNEbase 5:146994099-147547626
CIL_0000G0 CIL_0000G0_0003 CGP 5:147330741-147548502
CIL_0000G1 CIL_0000G1_0003 CGP 5:147430161-147726011

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000290 IMP deadenylation-dependent decapping of nuclear-transcribed mRNA
GO:0000932 IDA cytoplasmic mRNA processing body
GO:0004535 IEA poly(A)-specific ribonuclease activity
GO:0004672 IEA protein kinase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0006397 IEA mRNA processing
GO:0006468 IEA protein phosphorylation
GO:0006605 IDA protein targeting
GO:0010606 IDA positive regulation of cytoplasmic mRNA processing body assembly
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0031251 ISS PAN complex
GO:0046872 IEA metal ion binding
GO:0090503 IEA RNA phosphodiester bond hydrolysis, exonucleolytic

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000031637 pan3 PAN3 poly(A) specific ribonuclease subunit homolog (S. cerevisiae) protein_coding Danio_rerio
ENSG00000152520 PAN3 PAN3 poly(A) specific ribonuclease subunit protein_coding Homo_sapiens

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