C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: alpha-2-macroglobulin
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000030111 A2m 10090 + 6:121636173-121679237 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000032203 A2m-201 121636173-121679237 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000032203
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000032203 23.132±23.13 3.355±1.90 0.012±0.01 1.700±0.99 0.030±0.02 0.037±0.02 0.179±0.07 0.162±0.08 86.615±144.51 0.086±0.03 0.010±0.01 3.571±4.07 24.768±19.36 0.157±0.09

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000TB CIL_0000TB_000A CGP 6:121636173-121889057

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001869 IEA negative regulation of complement activation, lectin pathway
GO:0002020 IEA protease binding
GO:0004867 IEA serine-type endopeptidase inhibitor activity
GO:0005102 IEA receptor binding
GO:0005515 IPI protein binding
GO:0007565 IEA female pregnancy
GO:0010951 IEA negative regulation of endopeptidase activity
GO:0019838 IEA growth factor binding
GO:0019899 IEA enzyme binding
GO:0019959 IEA interleukin-8 binding
GO:0019966 IEA interleukin-1 binding
GO:0030414 TAS peptidase inhibitor activity
GO:0043120 IEA tumor necrosis factor binding
GO:0048306 IEA calcium-dependent protein binding
GO:0048863 IDA stem cell differentiation
GO:0070062 IEA extracellular vesicular exosome
GO:0072562 IEA blood microparticle

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000008835 A2ML1 (1 of 12) alpha-2-macroglobulin-like 1 protein_coding Danio_rerio
ENSDARG00000041645 A2ML1 (2 of 12) alpha-2-macroglobulin-like 1 protein_coding Danio_rerio
ENSDARG00000041685 A2ML1 (3 of 12) alpha-2-macroglobulin-like 1 protein_coding Danio_rerio
ENSDARG00000056314 a2ml alpha-2-macroglobulin-like protein_coding Danio_rerio
ENSDARG00000074764 A2ML1 (5 of 12) alpha-2-macroglobulin-like 1 protein_coding Danio_rerio
ENSDARG00000075737 A2ML1 (6 of 12) alpha-2-macroglobulin-like 1 protein_coding Danio_rerio
ENSDARG00000076366 A2ML1 (7 of 12) alpha-2-macroglobulin-like 1 protein_coding Danio_rerio
ENSDARG00000076771 A2ML1 (8 of 12) alpha-2-macroglobulin-like 1 protein_coding Danio_rerio
ENSDARG00000077171 A2ML1 (9 of 12) alpha-2-macroglobulin-like 1 protein_coding Danio_rerio
ENSDARG00000078183 A2ML1 (10 of 12) alpha-2-macroglobulin-like 1 protein_coding Danio_rerio
ENSDARG00000078757 A2ML1 (11 of 12) alpha-2-macroglobulin-like 1 protein_coding Danio_rerio
ENSDARG00000093199 A2ML1 (12 of 12) alpha-2-macroglobulin-like 1 protein_coding Danio_rerio
ENSG00000175899 A2M alpha-2-macroglobulin protein_coding Homo_sapiens

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