C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: dystrophia myotonica-protein kinase
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000030409 Dmpk 10090 + 7:19083849-19093821 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000032568 Dmpk-001 19083849-19093821 protein_coding
  ENSMUST00000108473 Dmpk-003 19083885-19093821 protein_coding
  ENSMUST00000108474 Dmpk-002 19083941-19093821 protein_coding
  ENSMUST00000122999 Dmpk-008 19083868-19086961 protein_coding
  ENSMUST00000126264 Dmpk-017 19092218-19093771 processed_transcript
  ENSMUST00000128422 Dmpk-012 19087611-19091767 processed_transcript
  ENSMUST00000132115 Dmpk-014 19088185-19093044 processed_transcript
  ENSMUST00000135839 Dmpk-007 19086500-19093819 retained_intron
  ENSMUST00000137219 Dmpk-006 19086500-19093819 retained_intron
  ENSMUST00000140742 Dmpk-018 19092296-19093204 retained_intron
  ENSMUST00000142725 Dmpk-005 19086500-19093819 processed_transcript
  ENSMUST00000143938 Dmpk-015 19091483-19092361 retained_intron
  ENSMUST00000147215 Dmpk-010 19087269-19089132 processed_transcript
  ENSMUST00000148380 Dmpk-016 19091616-19092535 processed_transcript
  ENSMUST00000148472 Dmpk-013 19087746-19089358 retained_intron
  ENSMUST00000149188 Dmpk-009 19084710-19087701 processed_transcript
  ENSMUST00000152050 Dmpk-011 19087493-19088631 processed_transcript
  ENSMUST00000154199 Dmpk-004 19083870-19093821 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000032568ENSMUST00000108473ENSMUST00000108474ENSMUST00000126264ENSMUST00000132115ENSMUST00000135839ENSMUST00000137219ENSMUST00000140742ENSMUST00000142725ENSMUST00000149188ENSMUST00000154199
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000032568 44.006±6.25 49.043±4.49 104.319±16.82 3.085±0.59 24.196±2.21 55.867±11.09 117.222±17.71 2.772±0.38 4.921±0.81 18.839±1.53 66.104±5.45 35.597±6.43 5.582±5.16 4.045±0.94
ENSMUST00000108473 31.520±0.04 N/A 96.853±18.01 N/A N/A 50.995±7.24 N/A 2.195±0.66 N/A 11.844±1.61 N/A 20.950±4.00 4.694±2.61 N/A
ENSMUST00000108474 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 12.288±0.00 N/A N/A
ENSMUST00000126264 N/A N/A N/A N/A 38.584±1.13 N/A N/A 5.183±0.90 N/A N/A N/A N/A 5.608±1.23 11.677±0.94
ENSMUST00000132115 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 78.021±0.00 N/A N/A
ENSMUST00000135839 N/A N/A N/A N/A N/A N/A N/A N/A 2.144±0.50 N/A N/A N/A 2.572±0.00 N/A
ENSMUST00000137219 23.772±3.37 27.382±3.39 N/A 4.181±0.78 11.727±1.28 32.327±7.68 59.028±14.21 2.273±0.39 2.948±0.69 9.407±1.40 N/A 25.014±5.12 0.808±0.00 4.587±1.11
ENSMUST00000140742 N/A 85.823±2.72 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENSMUST00000142725 N/A 25.077±2.95 N/A N/A 11.545±1.32 26.665±0.00 N/A 1.631±0.00 2.414±0.10 N/A 28.298±1.57 N/A 0.890±0.00 N/A
ENSMUST00000149188 N/A N/A N/A 9.381±0.00 N/A N/A N/A N/A N/A N/A N/A 29.131±0.00 N/A 16.536±0.00
ENSMUST00000154199 23.051±4.00 N/A 81.019±13.34 3.055±0.28 13.067±1.11 33.721±0.00 65.787±9.19 1.845±0.39 2.675±0.79 8.167±1.22 29.082±7.02 14.933±0.46 3.218±2.82 3.011±0.28

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002028 IMP regulation of sodium ion transport
GO:0004674 ISS protein serine/threonine kinase activity
GO:0005515 IPI protein binding
GO:0005524 ISS ATP binding
GO:0005634 IEA nucleus
GO:0005789 IDA endoplasmic reticulum membrane
GO:0005829 IDA cytosol
GO:0005886 IDA plasma membrane
GO:0006468 ISS protein phosphorylation
GO:0006874 IMP cellular calcium ion homeostasis
GO:0006998 IMP nuclear envelope organization
GO:0008016 IDA regulation of heart contraction
GO:0008152 IEA metabolic process
GO:0010657 ISS muscle cell apoptotic process
GO:0010830 IMP regulation of myotube differentiation
GO:0014722 IMP regulation of skeletal muscle contraction by calcium ion signaling
GO:0014853 IMP regulation of excitatory postsynaptic membrane potential involved in skeletal muscle contraction
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0017020 ISS myosin phosphatase regulator activity
GO:0031072 IEA heat shock protein binding
GO:0031307 IDA integral component of mitochondrial outer membrane
GO:0031965 IDA nuclear membrane
GO:0033017 IDA sarcoplasmic reticulum membrane
GO:0046872 IEA metal ion binding
GO:0051823 IMP regulation of synapse structural plasticity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000074914 DMPK dystrophia myotonica-protein kinase protein_coding Danio_rerio
ENSG00000104936 DMPK dystrophia myotonica-protein kinase protein_coding Homo_sapiens

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