C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: a disintegrin and metallopeptidase domain 18
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000031552 Adam18 10090 - 8:24602246-24674755 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000033957 Adam18-001 24602246-24674755 protein_coding
  ENSMUST00000138232 Adam18-002 24602250-24628254 processed_transcript
  ENSMUST00000173833 Adam18-003 24602246-24674755 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainBreastColonHeartKidneyLiverLungOvaryPlacentaTestisENSMUST00000033957ENSMUST00000138232ENSMUST00000173833
Transcript ID Brain Breast Colon Heart Kidney Liver Lung Ovary Placenta Testis
ENSMUST00000033957 N/A N/A N/A N/A N/A N/A N/A N/A N/A 41.131±11.65
ENSMUST00000138232 N/A N/A N/A N/A N/A N/A N/A 0.360±0.00 0.114±0.00 N/A
ENSMUST00000173833 0.010±0.00 0.028±0.01 0.058±0.03 0.015±0.00 0.017±0.00 0.003±0.00 0.092±0.05 0.012±0.00 0.005±0.00 9.671±2.47

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004222 IEA metalloendopeptidase activity
GO:0005178 ISS integrin binding
GO:0005575 ND cellular_component
GO:0005576 IEA extracellular region
GO:0006508 IEA proteolysis
GO:0007275 IEA multicellular organismal development
GO:0007283 IEA spermatogenesis
GO:0008270 IEA zinc ion binding
GO:0016021 IEA integral component of membrane
GO:0030154 IEA cell differentiation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000088127 ADAM2 ADAM metallopeptidase domain 2 protein_coding Danio_rerio
ENSG00000168619 ADAM18 ADAM metallopeptidase domain 18 protein_coding Homo_sapiens

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