C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: POU domain, class 4, transcription factor 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000031688 Pou4f2 10090 - 8:78433010-78436645 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000034115 Pou4f2-001 78433010-78436645 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainLiverOvaryPlacentaTestisENSMUST00000034115
Transcript ID Adipose Adrenal Brain Liver Ovary Placenta Testis
ENSMUST00000034115 0.010±0.00 0.023±0.00 2.272±1.70 0.027±0.03 0.048±0.04 0.007±0.00 0.019±0.01

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007K4 CIL_0007K4_0002 UCNEbase 8:78112601-78725703

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IMP negative regulation of transcription from RNA polymerase II promoter
GO:0000165 ISS MAPK cascade
GO:0000978 IEA RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001077 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0001078 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription
GO:0003682 IDA chromatin binding
GO:0003700 TAS sequence-specific DNA binding transcription factor activity
GO:0005634 IDA nucleus
GO:0006351 IEA transcription, DNA-templated
GO:0007399 IEA nervous system development
GO:0007409 IMP axonogenesis
GO:0007411 IMP axon guidance
GO:0007605 IGI sensory perception of sound
GO:0030182 IGI neuron differentiation
GO:0030520 ISS intracellular estrogen receptor signaling pathway
GO:0031290 IGI retinal ganglion cell axon guidance
GO:0045597 IMP positive regulation of cell differentiation
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0048675 IGI axon extension
GO:0050885 IGI neuromuscular process controlling balance
GO:0060041 IMP retina development in camera-type eye

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000069737 pou4f2 POU domain, class 4, transcription factor 2 protein_coding Danio_rerio
ENSG00000151615 POU4F2 POU class 4 homeobox 2 protein_coding Homo_sapiens

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