C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: RAS protein-specific guanine nucleotide-releasing factor 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000032356 Rasgrf1 10090 + 9:89909908-90026977 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000034909 Rasgrf1-002 89909909-89915834 protein_coding
  ENSMUST00000034912 Rasgrf1-001 89909909-90026977 protein_coding
  ENSMUST00000189545 Rasgrf1-003 89909908-89915847 protein_coding
  ENSMUST00000190073 Rasgrf1-004 89909912-89926740 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000034909ENSMUST00000034912ENSMUST00000189545
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000034909 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.038±0.00 N/A N/A N/A
ENSMUST00000034912 0.180±0.20 1.897±0.63 0.164±0.00 60.495±84.99 2.395±0.41 0.032±0.01 0.015±0.00 0.010±0.00 0.012±0.01 0.192±0.12 0.010±0.00 0.212±0.11 0.352±0.24 0.444±0.22
ENSMUST00000189545 0.210±0.20 2.514±0.60 0.226±0.03 0.836±0.01 2.742±0.32 0.011±0.00 0.005±0.00 0.009±0.01 0.009±0.01 0.163±0.01 0.011±0.00 0.079±0.03 0.138±0.07 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000587 CIL_000587_0002 CGP 9:89728249-90026977
CIL_00058A CIL_00058A_0002 CGP 9:89909908-90076089

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005089 IEA Rho guanyl-nucleotide exchange factor activity
GO:0005515 IPI protein binding
GO:0005829 IDA cytosol
GO:0007264 IEA small GTPase mediated signal transduction
GO:0008283 IMP cell proliferation
GO:0030426 IDA growth cone
GO:0031175 IDA neuron projection development
GO:0032320 IDA positive regulation of Ras GTPase activity
GO:0032863 IDA activation of Rac GTPase activity
GO:0035020 IDA regulation of Rac protein signal transduction
GO:0035254 IPI glutamate receptor binding
GO:0046578 IDA regulation of Ras protein signal transduction
GO:0046579 ISS positive regulation of Ras protein signal transduction
GO:0048167 ISS regulation of synaptic plasticity
GO:0048168 IMP regulation of neuronal synaptic plasticity
GO:2000310 IGI regulation of N-methyl-D-aspartate selective glutamate receptor activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000073824 RASGRF1 Ras protein-specific guanine nucleotide-releasing factor 1 protein_coding Danio_rerio
ENSG00000058335 RASGRF1 Ras protein-specific guanine nucleotide-releasing factor 1 protein_coding Homo_sapiens

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