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Institute of Cardiovascular Regeneration Webtool Repository

C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: cathepsin H
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000032359 Ctsh 10090 + 9:90054152-90076089 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000034915 Ctsh-001 90054267-90076089 protein_coding
  ENSMUST00000123320 Ctsh-003 90054538-90076087 nonsense_mediated_decay
  ENSMUST00000127842 Ctsh-002 90054506-90076087 retained_intron
  ENSMUST00000132718 Ctsh-004 90054152-90065422 protein_coding
  ENSMUST00000142750 Ctsh-006 90062522-90071885 retained_intron
  ENSMUST00000143172 Ctsh-005 90054537-90064239 protein_coding
  ENSMUST00000151219 Ctsh-007 90071696-90075749 retained_intron
  ENSMUST00000185459 Ctsh-011 90054559-90075741 protein_coding
  ENSMUST00000186126 Ctsh-008 90054521-90055338 retained_intron
  ENSMUST00000187437 Ctsh-009 90060153-90061623 retained_intron
  ENSMUST00000190338 Ctsh-010 90054554-90067344 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000034915ENSMUST00000123320ENSMUST00000127842ENSMUST00000132718ENSMUST00000142750ENSMUST00000151219ENSMUST00000185459
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000034915 26.450±5.40 17.588±4.88 51.111±5.19 N/A 23.507±3.30 10.572±4.43 6.194±2.38 23.200±0.00 37.684±23.83 34.489±1.64 0.715±0.14 10.642±4.39 99.204±28.15 2.559±0.71
ENSMUST00000123320 N/A N/A 18.735±0.00 2.641±0.00 33.950±0.00 N/A 6.343±0.00 N/A 15.860±0.00 N/A 0.727±0.00 29.584±6.57 3.598±1.43 0.246±0.00
ENSMUST00000127842 2.578±0.38 1.655±0.00 N/A N/A 4.951±1.04 N/A 0.794±0.06 N/A N/A 6.266±0.89 N/A 2.401±0.00 N/A 0.049±0.00
ENSMUST00000132718 N/A 26.775±6.05 N/A N/A 51.225±4.99 26.460±5.34 N/A 39.423±3.63 43.488±0.00 64.753±9.44 N/A 21.018±3.00 N/A N/A
ENSMUST00000142750 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 15.158±0.89 N/A N/A
ENSMUST00000151219 N/A N/A N/A 5.805±0.00 N/A N/A N/A N/A N/A N/A N/A 31.762±0.00 22.164±18.28 5.745±0.00
ENSMUST00000185459 N/A N/A N/A N/A 14.750±0.00 N/A N/A N/A N/A N/A N/A 7.243±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00058A CIL_00058A_0002 CGP 9:89909908-90076089
CIL_00085Y CIL_00085Y_0002 VISTA 9:90013787-90616367

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001520 IEA outer dense fiber
GO:0001656 ISS metanephros development
GO:0001669 IEA acrosomal vesicle
GO:0001913 IGI T cell mediated cytotoxicity
GO:0002250 IEA adaptive immune response
GO:0002764 ISS immune response-regulating signaling pathway
GO:0004175 ISS endopeptidase activity
GO:0004177 ISS aminopeptidase activity
GO:0004197 IDA cysteine-type endopeptidase activity
GO:0004252 IMP serine-type endopeptidase activity
GO:0005515 IEA protein binding
GO:0005615 ISS extracellular space
GO:0005764 ISS lysosome
GO:0005829 ISS cytosol
GO:0005930 IEA axoneme
GO:0006508 ISS proteolysis
GO:0006915 IGI apoptotic process
GO:0006919 IGI activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0007283 IEA spermatogenesis
GO:0008233 IEA peptidase activity
GO:0008234 ISS cysteine-type peptidase activity
GO:0008284 IMP positive regulation of cell proliferation
GO:0008656 IGI cysteine-type endopeptidase activator activity involved in apoptotic process
GO:0010628 ISS positive regulation of gene expression
GO:0010634 IMP positive regulation of epithelial cell migration
GO:0010813 ISS neuropeptide catabolic process
GO:0010815 ISS bradykinin catabolic process
GO:0010952 IGI positive regulation of peptidase activity
GO:0016505 IGI peptidase activator activity involved in apoptotic process
GO:0030108 ISS HLA-A specific activating MHC class I receptor activity
GO:0030335 ISS positive regulation of cell migration
GO:0030984 IEA kininogen binding
GO:0031638 IMP zymogen activation
GO:0031648 IMP protein destabilization
GO:0032403 IEA protein complex binding
GO:0032526 IDA response to retinoic acid
GO:0033619 IMP membrane protein proteolysis
GO:0043066 IMP negative regulation of apoptotic process
GO:0043129 ISS surfactant homeostasis
GO:0043621 IEA protein self-association
GO:0045766 IMP positive regulation of angiogenesis
GO:0060448 IMP dichotomous subdivision of terminal units involved in lung branching
GO:0070062 IEA extracellular vesicular exosome
GO:0070324 ISS thyroid hormone binding
GO:0070371 ISS ERK1 and ERK2 cascade
GO:0097067 IEA cellular response to thyroid hormone stimulus
GO:0097208 ISS alveolar lamellar body
GO:2001235 IGI positive regulation of apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000041108 ctsh cathepsin H protein_coding Danio_rerio
ENSG00000103811 CTSH cathepsin H protein_coding Homo_sapiens

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