C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000032754 Slc8b1 10090 + 5:120511168-120534024 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000068326 Slc8b1-001 120511168-120534024 protein_coding
  ENSMUST00000076051 Slc8b1-003 120511252-120534020 protein_coding
  ENSMUST00000111889 Slc8b1-006 120513143-120533057 protein_coding
  ENSMUST00000111890 Slc8b1-002 120511235-120534019 protein_coding
  ENSMUST00000123326 Slc8b1-007 120520779-120522220 retained_intron
  ENSMUST00000140329 Slc8b1-005 120512868-120519751 protein_coding
  ENSMUST00000147496 Slc8b1-004 120511270-120513188 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000068326ENSMUST00000076051ENSMUST00000111889ENSMUST00000111890ENSMUST00000140329
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000068326 10.998±4.71 8.242±2.27 10.585±0.15 0.679±0.03 10.500±3.80 20.110±7.58 2.415±1.11 5.844±1.11 8.432±3.37 9.720±1.46 1.489±0.82 7.454±1.36 7.539±4.02 0.905±0.36
ENSMUST00000076051 6.112±1.22 6.786±2.00 4.533±0.38 0.352±0.06 5.194±1.42 10.561±2.69 2.070±0.39 3.850±0.54 4.124±2.85 4.985±1.13 1.492±0.51 4.642±1.96 7.501±5.30 0.405±0.27
ENSMUST00000111889 N/A N/A N/A 0.891±0.00 3.740±0.00 N/A N/A N/A N/A N/A N/A 2.561±0.00 3.796±0.00 0.510±0.00
ENSMUST00000111890 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.811±0.28 0.711±0.00 2.033±0.00 N/A
ENSMUST00000140329 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 39.560±17.10 0.512±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000842 CIL_000842_0002 VISTA 5:119987382-120588927

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005432 IDA calcium:sodium antiporter activity
GO:0005739 IDA mitochondrion
GO:0005743 IEA mitochondrial inner membrane
GO:0005783 IEA endoplasmic reticulum
GO:0005886 IDA plasma membrane
GO:0006851 IDA mitochondrial calcium ion transport
GO:0016021 IEA integral component of membrane
GO:0030061 ISS mitochondrial crista
GO:0032592 ISS integral component of mitochondrial membrane
GO:0035725 IDA sodium ion transmembrane transport
GO:0042383 IEA sarcolemma
GO:0042593 ISS glucose homeostasis
GO:0042803 IPI protein homodimerization activity
GO:0050796 ISS regulation of insulin secretion
GO:0050896 IEA response to stimulus
GO:0051480 IDA cytosolic calcium ion homeostasis
GO:0051560 IDA mitochondrial calcium ion homeostasis
GO:0070588 IDA calcium ion transmembrane transport
GO:0086036 IC regulation of cardiac muscle cell membrane potential
GO:0086038 IC calcium:sodium antiporter activity involved in regulation of cardiac muscle cell membrane potential

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000086905 FP103011.3 Uncharacterized protein protein_coding Danio_rerio
ENSG00000089060 SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1 protein_coding Homo_sapiens

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