C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: polycystic kidney disease 1 homolog
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000032855 Pkd1 10090 + 17:24549950-24596514 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000035565 Pkd1-201 24549950-24596514 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000035565
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000035565 15.587±2.22 10.158±1.50 9.631±1.51 10.103±1.89 15.175±6.91 14.553±2.36 6.976±1.79 5.390±1.88 1.536±0.61 25.361±5.10 2.702±0.61 24.844±9.97 4.069±1.49 3.825±1.59

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001502 IMP cartilage condensation
GO:0001568 IMP blood vessel development
GO:0001701 IGI in utero embryonic development
GO:0001822 IMP kidney development
GO:0001889 IGI liver development
GO:0001892 IMP embryonic placenta development
GO:0002133 IDA polycystin complex
GO:0005262 TAS calcium channel activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005737 IMP cytoplasm
GO:0005794 IEA Golgi apparatus
GO:0005886 IEA plasma membrane
GO:0005929 IDA cilium
GO:0006611 IMP protein export from nucleus
GO:0006807 IGI nitrogen compound metabolic process
GO:0006816 IMP calcium ion transport
GO:0007050 IDA cell cycle arrest
GO:0007204 IEA positive regulation of cytosolic calcium ion concentration
GO:0007218 IEA neuropeptide signaling pathway
GO:0007259 IDA JAK-STAT cascade
GO:0007507 IMP heart development
GO:0016021 IEA integral component of membrane
GO:0016323 IEA basolateral plasma membrane
GO:0016328 IEA lateral plasma membrane
GO:0016337 IMP single organismal cell-cell adhesion
GO:0018105 IMP peptidyl-serine phosphorylation
GO:0019901 IEA protein kinase binding
GO:0019904 IEA protein domain specific binding
GO:0021510 IEA spinal cord development
GO:0021915 IEA neural tube development
GO:0030246 IEA carbohydrate binding
GO:0031512 IDA motile primary cilium
GO:0031659 IEA positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle
GO:0032092 IMP positive regulation of protein binding
GO:0034405 IMP response to fluid shear stress
GO:0042994 IMP cytoplasmic sequestering of transcription factor
GO:0043588 IEA skin development
GO:0044325 IEA ion channel binding
GO:0045944 IEA positive regulation of transcription from RNA polymerase II promoter
GO:0048565 IEA digestive tract development
GO:0048754 IEA branching morphogenesis of an epithelial tube
GO:0048806 IEA genitalia development
GO:0050982 IMP detection of mechanical stimulus
GO:0051216 IEA cartilage development
GO:0060236 IMP regulation of mitotic spindle organization
GO:0060428 IEA lung epithelium development
GO:0060674 IMP placenta blood vessel development
GO:0061136 IMP regulation of proteasomal protein catabolic process
GO:0070062 IEA extracellular vesicular exosome
GO:0070588 TAS calcium ion transmembrane transport
GO:0072001 IGI renal system development
GO:0072164 IEA mesonephric tubule development
GO:0072177 IEA mesonephric duct development
GO:0072205 IEA metanephric collecting duct development
GO:0072218 IEA metanephric ascending thin limb development
GO:0072237 IEA metanephric proximal tubule development
GO:0072287 IEA metanephric distal tubule morphogenesis

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000030417 PKD1 polycystic kidney disease 1 (autosomal dominant) protein_coding Danio_rerio
ENSG00000008710 PKD1 polycystic kidney disease 1 (autosomal dominant) protein_coding Homo_sapiens

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