C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: cytochrome b5 reductase 4
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000032872 Cyb5r4 10090 + 9:87022014-87077774 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000168529 Cyb5r4-001 87022014-87077774 protein_coding
  ENSMUST00000174043 Cyb5r4-005 87027071-87062115 retained_intron
  ENSMUST00000174294 Cyb5r4-006 87058939-87077381 nonsense_mediated_decay
  ENSMUST00000174540 Cyb5r4-004 87029571-87047501 retained_intron
  ENSMUST00000174724 Cyb5r4-002 87022087-87068248 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000168529ENSMUST00000174043ENSMUST00000174294
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000168529 4.195±1.62 14.491±8.83 7.631±1.50 3.296±0.00 4.944±2.52 2.658±0.00 2.085±0.48 4.698±3.53 4.939±1.99 6.035±3.45 8.143±1.50 8.899±2.47 8.937±0.79 8.675±1.02
ENSMUST00000174043 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.406±0.08 N/A N/A
ENSMUST00000174294 N/A N/A N/A 15.854±0.00 4.558±0.08 N/A 4.820±0.90 7.244±1.62 5.410±1.55 5.817±0.24 N/A N/A 6.695±0.23 7.397±0.36

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000819 CIL_000819_0002 VISTA 9:86855250-87464091
CIL_000676 CIL_000676_0002 CGP 9:87015537-87077774
CIL_00071Q CIL_00071Q_0002 CGP 9:87022014-87184045

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003958 IEA NADPH-hemoprotein reductase activity
GO:0004128 ISA cytochrome-b5 reductase activity, acting on NAD(P)H
GO:0005515 IPI protein binding
GO:0005737 ISA cytoplasm
GO:0005783 IDA endoplasmic reticulum
GO:0006091 IEA generation of precursor metabolites and energy
GO:0006739 IEA NADP metabolic process
GO:0006801 IEA superoxide metabolic process
GO:0016174 IEA NAD(P)H oxidase activity
GO:0016653 IEA oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor
GO:0020037 ISA heme binding
GO:0030073 IMP insulin secretion
GO:0042168 ISA heme metabolic process
GO:0042593 IMP glucose homeostasis
GO:0046677 IMP response to antibiotic
GO:0046872 IEA metal ion binding
GO:0048468 IMP cell development
GO:0048471 IEA perinuclear region of cytoplasm
GO:0050660 IEA flavin adenine dinucleotide binding
GO:0055114 IEA oxidation-reduction process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000020898 cyb5r4 cytochrome b5 reductase 4 protein_coding Danio_rerio
ENSG00000065615 CYB5R4 cytochrome b5 reductase 4 protein_coding Homo_sapiens

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