C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: RAS, guanyl releasing protein 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000032946 Rasgrp2 10090 + 19:6399340-6415216 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000035716 Rasgrp2-001 6400562-6415216 protein_coding
  ENSMUST00000113467 Rasgrp2-017 6400623-6403612 protein_coding
  ENSMUST00000113468 Rasgrp2-023 6399746-6403485 protein_coding
  ENSMUST00000113469 Rasgrp2-020 6401718-6403638 protein_coding
  ENSMUST00000113471 Rasgrp2-018 6401702-6403638 protein_coding
  ENSMUST00000113472 Rasgrp2-002 6400113-6403638 protein_coding
  ENSMUST00000113475 Rasgrp2-022 6399456-6403633 protein_coding
  ENSMUST00000113476 Rasgrp2-021 6399340-6415210 protein_coding
  ENSMUST00000122930 Rasgrp2-010 6401695-6402446 processed_transcript
  ENSMUST00000123661 Rasgrp2-009 6399917-6402446 processed_transcript
  ENSMUST00000127021 Rasgrp2-024 6400533-6415205 nonsense_mediated_decay
  ENSMUST00000130480 Rasgrp2-013 6402918-6404971 retained_intron
  ENSMUST00000133968 Rasgrp2-019 6401719-6403638 processed_transcript
  ENSMUST00000135532 Rasgrp2-003 6404741-6409668 retained_intron
  ENSMUST00000138555 Rasgrp2-011 6400564-6404824 protein_coding
  ENSMUST00000139522 Rasgrp2-014 6399874-6404337 nonsense_mediated_decay
  ENSMUST00000145611 Rasgrp2-007 6400527-6402430 processed_transcript
  ENSMUST00000146601 Rasgrp2-005 6399864-6402574 protein_coding
  ENSMUST00000146831 Rasgrp2-008 6400547-6404421 protein_coding
  ENSMUST00000148906 Rasgrp2-015 6404582-6407061 retained_intron
  ENSMUST00000149205 Rasgrp2-004 6408405-6415211 processed_transcript
  ENSMUST00000150713 Rasgrp2-006 6399868-6403478 protein_coding
  ENSMUST00000152022 Rasgrp2-016 6404827-6414041 retained_intron
  ENSMUST00000167240 Rasgrp2-201 6400583-6415215 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000035716ENSMUST00000113471ENSMUST00000113472ENSMUST00000113476ENSMUST00000130480ENSMUST00000135532ENSMUST00000138555ENSMUST00000146601ENSMUST00000149205ENSMUST00000152022ENSMUST00000167240
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000035716 10.440±0.00 5.543±1.93 N/A 5.463±0.00 16.672±2.22 N/A N/A 4.207±0.00 1.686±0.00 9.758±3.36 N/A 3.731±1.07 N/A N/A
ENSMUST00000113471 62.712±0.00 N/A N/A N/A N/A N/A N/A N/A 25.474±17.15 N/A N/A 11.685±0.00 12.895±3.04 1.276±0.00
ENSMUST00000113472 N/A 4.429±0.19 N/A N/A N/A N/A N/A N/A N/A N/A 1.841±0.35 N/A N/A 0.193±0.11
ENSMUST00000113476 3.866±0.00 N/A N/A 2.316±0.11 N/A 1.994±0.00 N/A N/A N/A N/A 1.970±0.00 2.153±0.00 N/A 0.468±0.01
ENSMUST00000130480 N/A N/A N/A 20.690±0.00 N/A N/A N/A N/A N/A N/A N/A N/A 3.046±0.00 N/A
ENSMUST00000135532 N/A 9.191±3.47 N/A N/A N/A N/A N/A N/A N/A N/A N/A 9.179±0.00 N/A N/A
ENSMUST00000138555 N/A N/A N/A N/A 21.109±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENSMUST00000146601 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 23.113±5.74 N/A N/A
ENSMUST00000149205 N/A N/A N/A 23.921±0.00 N/A N/A N/A N/A N/A N/A N/A 8.927±0.00 4.266±0.28 0.371±0.00
ENSMUST00000152022 2.593±0.86 N/A 2.069±0.05 0.510±0.17 N/A N/A N/A 1.186±0.04 1.084±0.58 3.902±0.89 0.581±0.40 1.186±0.48 0.601±0.25 0.107±0.02
ENSMUST00000167240 15.738±0.00 N/A N/A 2.003±0.00 N/A N/A 5.439±0.05 3.644±0.00 8.236±4.72 N/A 2.632±0.68 N/A 3.375±1.30 0.315±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005085 IEA guanyl-nucleotide exchange factor activity
GO:0005509 IEA calcium ion binding
GO:0005622 IEA intracellular
GO:0005829 ISS cytosol
GO:0005886 ISS plasma membrane
GO:0007264 IEA small GTPase mediated signal transduction
GO:0030054 IEA cell junction
GO:0032854 IEA positive regulation of Rap GTPase activity
GO:0043005 IEA neuron projection
GO:0043547 IEA positive regulation of GTPase activity
GO:0045202 IEA synapse
GO:0051056 IEA regulation of small GTPase mediated signal transduction
GO:0071277 IEA cellular response to calcium ion

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000062328 rasgrp2 RAS guanyl releasing protein 2 (calcium and DAG-regulated) protein_coding Danio_rerio
ENSDARG00000087154 RASGRP2 (2 of 2) RAS guanyl releasing protein 2 (calcium and DAG-regulated) protein_coding Danio_rerio
ENSG00000068831 RASGRP2 RAS guanyl releasing protein 2 (calcium and DAG-regulated) protein_coding Homo_sapiens

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