C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: RAS-related C3 botulinum substrate 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000033220 Rac2 10090 - 15:78559169-78572783 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000043214 Rac2-201 78559169-78572783 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000043214
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000043214 13.841±5.23 7.684±1.10 5.374±0.47 0.625±0.31 134.640±77.78 15.862±2.88 3.101±2.16 7.385±5.55 26.018±19.76 17.181±8.66 0.770±1.38 9.139±5.33 0.722±0.53 1.222±0.33

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00036V CIL_00036V_0002 CGP 15:78537015-78572783
CIL_000486 CIL_000486_0002 CGP 15:78559169-78622019

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003924 IDA GTPase activity
GO:0005525 IEA GTP binding
GO:0005635 IDA nuclear envelope
GO:0005737 IDA cytoplasm
GO:0005829 IEA cytosol
GO:0005884 IEA actin filament
GO:0005925 IEA focal adhesion
GO:0006184 IDA GTP catabolic process
GO:0006935 IDA chemotaxis
GO:0007015 IEA actin filament organization
GO:0007186 IGI G-protein coupled receptor signaling pathway
GO:0007264 IEA small GTPase mediated signal transduction
GO:0008284 IGI positive regulation of cell proliferation
GO:0010592 IMP positive regulation of lamellipodium assembly
GO:0010810 IEA regulation of cell-substrate adhesion
GO:0016020 IDA membrane
GO:0030027 IEA lamellipodium
GO:0030031 IDA cell projection assembly
GO:0030036 IDA actin cytoskeleton organization
GO:0045453 IEA bone resorption
GO:0060263 IEA regulation of respiratory burst
GO:0070062 IEA extracellular vesicular exosome
GO:0071593 IEA lymphocyte aggregation
GO:0090023 IMP positive regulation of neutrophil chemotaxis
GO:1902622 IEA regulation of neutrophil migration

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000038010 rac2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) protein_coding Danio_rerio
ENSG00000128340 RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) protein_coding Homo_sapiens

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