C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: asp (abnormal spindle)-like, microcephaly associated (Drosophila)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000033952 Aspm 10090 + 1:139454773-139494090 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000053364 Aspm-001 139454775-139494090 protein_coding
  ENSMUST00000097554 Aspm-002 139454775-139494083 protein_coding
  ENSMUST00000128413 Aspm-004 139454819-139457134 processed_transcript
  ENSMUST00000155402 Aspm-003 139454773-139474334 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000053364ENSMUST00000097554ENSMUST00000128413ENSMUST00000155402
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000053364 0.310±0.27 0.102±0.04 0.105±0.00 1.381±1.04 0.167±0.05 0.636±0.15 0.014±0.00 0.031±0.01 2.567±2.51 0.138±0.07 0.007±0.00 1.529±0.46 1.714±1.10 0.477±0.42
ENSMUST00000097554 N/A N/A 0.041±0.00 0.027±0.00 N/A 0.308±0.00 0.029±0.02 N/A 0.029±0.01 0.087±0.01 0.010±0.01 0.498±0.00 N/A N/A
ENSMUST00000128413 N/A 0.156±0.07 N/A N/A N/A 0.382±0.08 N/A N/A 0.017±0.00 N/A N/A N/A N/A N/A
ENSMUST00000155402 N/A 0.205±0.05 N/A N/A 0.112±0.06 N/A N/A 0.006±0.00 N/A N/A N/A N/A N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000922 IDA spindle pole
GO:0001764 IGI neuron migration
GO:0002052 IGI positive regulation of neuroblast proliferation
GO:0005516 IDA calmodulin binding
GO:0005634 IEA nucleus
GO:0005737 IDA cytoplasm
GO:0005874 IDA microtubule
GO:0007067 IEA mitotic nuclear division
GO:0007283 IMP spermatogenesis
GO:0007420 IMP brain development
GO:0008584 IMP male gonad development
GO:0021873 IMP forebrain neuroblast division
GO:0021987 IMP cerebral cortex development
GO:0030496 IDA midbody
GO:0045665 IMP negative regulation of neuron differentiation
GO:0045769 IMP negative regulation of asymmetric cell division
GO:0048477 IMP oogenesis
GO:0048589 IMP developmental growth
GO:0051661 IMP maintenance of centrosome location
GO:0072687 IDA meiotic spindle
GO:0090263 IGI positive regulation of canonical Wnt signaling pathway
GO:0090306 IMP spindle assembly involved in meiosis
GO:0097150 IMP neuronal stem cell maintenance
GO:0097431 IDA mitotic spindle pole

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000071442 aspm asp (abnormal spindle)-like, microcephaly associated (Drosophila) protein_coding Danio_rerio
ENSG00000066279 ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila) protein_coding Homo_sapiens

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