C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: FYVE, RhoGEF and PH domain containing 5
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000034037 Fgd5 10090 + 6:91978878-92076004 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000089334 Fgd5-001 91978878-92076004 protein_coding
  ENSMUST00000113466 Fgd5-201 91987110-92076004 protein_coding
  ENSMUST00000130369 Fgd5-003 92071188-92074215 processed_transcript
  ENSMUST00000146743 Fgd5-002 92067429-92076004 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000089334ENSMUST00000113466ENSMUST00000146743
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000089334 4.142±1.36 3.095±0.48 1.702±0.49 1.881±1.36 2.397±1.11 1.485±0.35 3.073±0.30 3.060±0.49 0.577±0.25 10.786±1.20 1.444±0.49 3.017±0.76 1.161±1.09 0.283±0.05
ENSMUST00000113466 N/A N/A N/A 0.351±0.00 0.440±0.00 N/A N/A N/A 0.227±0.00 N/A 0.955±0.32 2.980±1.41 0.222±0.00 0.106±0.00
ENSMUST00000146743 4.086±2.16 N/A 2.491±0.06 1.781±0.55 1.254±0.00 1.126±0.09 1.646±0.37 1.906±0.20 0.525±0.24 N/A 1.099±0.43 2.370±0.47 1.150±0.42 0.170±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007GJ CIL_0007GJ_0002 CGP 6:91914759-92076004
CIL_0005AG CIL_0005AG_0002 CGP 6:91978878-92173057

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003674 ND molecular_function
GO:0005089 IEA Rho guanyl-nucleotide exchange factor activity
GO:0005515 IEA protein binding
GO:0005575 ND cellular_component
GO:0008150 ND biological_process
GO:0032321 IEA positive regulation of Rho GTPase activity
GO:0046872 IEA metal ion binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000089622 fgd5b FYVE, RhoGEF and PH domain containing 5b protein_coding Danio_rerio
ENSG00000154783 FGD5 FYVE, RhoGEF and PH domain containing 5 protein_coding Homo_sapiens

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