C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: uveal autoantigen with coiled-coil domains and ankyrin repeats
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000034485 Uaca 10090 + 9:60794548-60880370 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000050183 Uaca-201 60794548-60880370 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000050183
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000050183 4.364±1.86 5.984±1.03 7.535±1.39 3.810±1.95 3.159±1.36 5.488±3.26 4.700±0.60 6.037±2.21 1.129±0.24 4.344±2.47 34.674±3.47 3.507±2.25 57.548±46.94 11.725±16.10

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005635 IDA nuclear envelope
GO:0005737 IDA cytoplasm
GO:0005739 IEA mitochondrion
GO:0005829 IDA cytosol
GO:0005856 IEA cytoskeleton
GO:0008630 IMP intrinsic apoptotic signaling pathway in response to DNA damage
GO:0008631 IMP intrinsic apoptotic signaling pathway in response to oxidative stress
GO:0009411 IMP response to UV
GO:0016020 IDA membrane
GO:0042307 IMP positive regulation of protein import into nucleus
GO:0042347 IMP negative regulation of NF-kappaB import into nucleus
GO:0043065 IMP positive regulation of apoptotic process
GO:0043280 IDA positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0043293 IDA apoptosome
GO:0048471 IDA perinuclear region of cytoplasm
GO:0050728 IMP negative regulation of inflammatory response
GO:0070062 IEA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000060238 UACA (1 of 2) uveal autoantigen with coiled-coil domains and ankyrin repeats protein_coding Danio_rerio
ENSG00000137831 UACA uveal autoantigen with coiled-coil domains and ankyrin repeats protein_coding Homo_sapiens

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